PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30067361-3	2018	The careful design, selection, and evaluation of substituents appended to the C-3 and C-17 positions of the natural product betulinic acid (3) was critical in attaining a molecule with the desired virological and pharmacokinetic profile.	betulinic acid	124-138	complement C3	Homo sapiens	78-81	
22704237-1	2012	A new series of betulinic acid and betulin derivatives were synthesized by introducing a D-glycerol moiety at the C-3 and/or C-28 positions of the lupane skeleton.	betulinic acid	16-30	complement C3	Homo sapiens	114-117	
16314103-1	2006	Betulinic acid (BA) derivatives with a side chain at C-3 can inhibit HIV-1 maturation.	betulinic acid	0-14	complement C3	Homo sapiens	53-56	
17851638-0	2008	Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.	betulinic acid	43-57	complement C3	Homo sapiens	30-33	
18752941-1	2008	A new series of betulinic acid derivatives have been synthesized by introducing heterocyclic ring between C-2 and C-3 positions of betulinic acid.	betulinic acid	16-30	complement C3	Homo sapiens	114-117	
18752941-1	2008	A new series of betulinic acid derivatives have been synthesized by introducing heterocyclic ring between C-2 and C-3 positions of betulinic acid.	betulinic acid	131-145	complement C3	Homo sapiens	114-117	
16314103-1	2006	Betulinic acid (BA) derivatives with a side chain at C-3 can inhibit HIV-1 maturation.	betulinic acid	16-18	complement C3	Homo sapiens	53-56	
16314103-3	2006	In order to combine the anti-maturation and anti-entry activities in a single molecule, new bi-functional BA derivatives containing side chains at C-3 and C-28 have been synthesized.	betulinic acid	106-108	complement C3	Homo sapiens	147-150	
14505668-1	2003	Betulin and betulinic acid have been modified at the C-3 and C-28 positions and the antiviral activity of derivatives has been evaluated in vitro.	betulinic acid	12-26	complement C3	Homo sapiens	53-56	
9873420-1	1998	Betulinic acid has been modified at C-3, C-20, and C-28 positions and the toxicity of the derivatives has been evaluated against cultured human melanoma (MEL-2) and human epidermoid carcinoma of the mouth (KB) cell lines.	betulinic acid	0-14	complement C3	Homo sapiens	36-39