PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17851638-0 2008 Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity. betulinic acid 43-57 complement C3 Homo sapiens 30-33 18752941-1 2008 A new series of betulinic acid derivatives have been synthesized by introducing heterocyclic ring between C-2 and C-3 positions of betulinic acid. betulinic acid 16-30 complement C3 Homo sapiens 114-117 18752941-1 2008 A new series of betulinic acid derivatives have been synthesized by introducing heterocyclic ring between C-2 and C-3 positions of betulinic acid. betulinic acid 131-145 complement C3 Homo sapiens 114-117 30067361-3 2018 The careful design, selection, and evaluation of substituents appended to the C-3 and C-17 positions of the natural product betulinic acid (3) was critical in attaining a molecule with the desired virological and pharmacokinetic profile. betulinic acid 124-138 complement C3 Homo sapiens 78-81 22704237-1 2012 A new series of betulinic acid and betulin derivatives were synthesized by introducing a D-glycerol moiety at the C-3 and/or C-28 positions of the lupane skeleton. betulinic acid 16-30 complement C3 Homo sapiens 114-117 14505668-1 2003 Betulin and betulinic acid have been modified at the C-3 and C-28 positions and the antiviral activity of derivatives has been evaluated in vitro. betulinic acid 12-26 complement C3 Homo sapiens 53-56 16314103-1 2006 Betulinic acid (BA) derivatives with a side chain at C-3 can inhibit HIV-1 maturation. betulinic acid 0-14 complement C3 Homo sapiens 53-56 16314103-1 2006 Betulinic acid (BA) derivatives with a side chain at C-3 can inhibit HIV-1 maturation. betulinic acid 16-18 complement C3 Homo sapiens 53-56 16314103-3 2006 In order to combine the anti-maturation and anti-entry activities in a single molecule, new bi-functional BA derivatives containing side chains at C-3 and C-28 have been synthesized. betulinic acid 106-108 complement C3 Homo sapiens 147-150 9873420-1 1998 Betulinic acid has been modified at C-3, C-20, and C-28 positions and the toxicity of the derivatives has been evaluated against cultured human melanoma (MEL-2) and human epidermoid carcinoma of the mouth (KB) cell lines. betulinic acid 0-14 complement C3 Homo sapiens 36-39