PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17620440-3	2007	Here, we describe six BA derivatives that are markedly more potent than BA for inhibiting inducible nitric oxide synthase, activating phase 2 cytoprotective enzymes, and inducing apoptosis in cancer cells and in Bax/Bak(-/-) fibroblasts, which lack two key proteins involved in the intrinsic, mitochondrial-dependent apoptotic pathway.	betulinic acid	22-24	BCL2 antagonist/killer 1	Homo sapiens	216-219	
19115109-0	2009	Betulinic acid induces cytochrome c release and apoptosis in a Bax/Bak-independent, permeability transition pore dependent fashion.	betulinic acid	0-14	BCL2 antagonist/killer 1	Homo sapiens	67-70	
34064489-6	2021	In addition, BA triggered a dose-dependent cytotoxic effect characterized by apoptotic features: morphological alterations (nuclear fragmentation, apoptotic bodies) and the upregulation of pro-apoptotic markers mRNA expression (Bax, Bad and Bak).	betulinic acid	13-15	BCL2 antagonist/killer 1	Homo sapiens	241-244	
22526391-0	2012	Betulinic acid induces Bax/Bak-independent cytochrome c release in human nasopharyngeal carcinoma cells.	betulinic acid	0-14	BCL2 antagonist/killer 1	Homo sapiens	27-30