PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25361208-5 2014 Based on IC50 values under normoxic conditions, we detected a 1.3-2.9-fold higher cytotoxicity of the BA derivatives B10 and NVX-207, respectively, compared to BA. betulinic acid 102-104 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 117-120 24743710-0 2014 Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid. betulinic acid 82-96 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 48-51 24743710-1 2014 B10 is a glycosylated derivative of betulinic acid with promising activity against glioma cells. betulinic acid 36-50 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 0-3 22343715-0 2012 Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process. betulinic acid 71-85 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 37-40 23000516-2 2013 Here, we discover that the PI3K inhibitor GDC-0941 acts in concert with the natural compound B10, a glycosylated derivative of betulinic acid, to induce cell death in glioblastoma cells. betulinic acid 127-141 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 93-96 22343715-2 2012 B10 is a semi-synthetic glycosylated derivative of BA selected for its enhanced cytotoxic activity. betulinic acid 51-53 ectonucleotide pyrophosphatase/phosphodiesterase 3 Homo sapiens 0-3