PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15057642-5	2004	Published data suggest that betulinic acid induces apoptosis in sensitive cells in a p53- and CD95-independent fashion.	betulinic acid	28-42	Fas cell surface death receptor	Homo sapiens	94-98	
9865749-0	1998	Correspondence re: S. Fulda et al., Betulinic acid triggers CD95 (Apo1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.	betulinic acid	36-50	Fas cell surface death receptor	Homo sapiens	60-64	
11511312-12	2001	In fact, betulinic acid induced mitochondrial cytochrome c release and DNA fragmentation in both CD95-resistant and CD95-sensitive melanoma cell populations, independent of the Bax/Bcl-2 ratio.	betulinic acid	9-23	Fas cell surface death receptor	Homo sapiens	97-101	
11511312-12	2001	In fact, betulinic acid induced mitochondrial cytochrome c release and DNA fragmentation in both CD95-resistant and CD95-sensitive melanoma cell populations, independent of the Bax/Bcl-2 ratio.	betulinic acid	9-23	Fas cell surface death receptor	Homo sapiens	116-120	
9865749-0	1998	Correspondence re: S. Fulda et al., Betulinic acid triggers CD95 (Apo1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.	betulinic acid	36-50	Fas cell surface death receptor	Homo sapiens	66-70	
9766678-2	1998	We investigated the sequence of these events in SHEP neuroblastoma cells transfected with Bcl-2 or Bcl-X(L) using two different drugs, namely, doxorubicin (Doxo), which activates the CD95/CD95 ligand (CD95-L) system, and betulinic acid (Bet A), which does not enhance the expression of CD95 or CD95-L and which, as shown here, directly targets mitochondria.	betulinic acid	221-235	Fas cell surface death receptor	Homo sapiens	183-187	
9354463-3	1997	BA-induced apoptosis was independent of CD95-ligand/receptor interaction and accumulation of wild-type p53 protein, but it critically depended on activation of caspases (interleukin 1beta-converting enzyme/Ced-3-like proteases).	betulinic acid	0-2	Fas cell surface death receptor	Homo sapiens	40-44	
9354463-0	1997	Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.	betulinic acid	0-14	Fas cell surface death receptor	Homo sapiens	24-28	
9354463-0	1997	Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors.	betulinic acid	0-14	Fas cell surface death receptor	Homo sapiens	30-35