PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15831282-8 2005 Conversely, betulinic acid significantly triggered caspase-9 and -3 activation. betulinic acid 12-26 caspase 9 Homo sapiens 51-67 15821941-5 2005 RESULTS: Treatment with betulinic acid caused an immediate disruption of mitochondrial transmembrane potential and activation of the "death enzymes" caspase-9 and -3. betulinic acid 24-38 caspase 9 Homo sapiens 149-165 15492260-5 2004 Treatment with cisplatin, camptothecin, etoposide, betulinic acid, celecoxib, 1400W, and staurosporine promoted enzymatic activity not only of caspases -2, -8, and -3 but also of caspase-9 in both APAF-1(+) and APAF-1(-) tumor cells. betulinic acid 51-65 caspase 9 Homo sapiens 179-188 15659823-7 2004 Treatment with betulinic acid resulted in the induction of type II apoptosis measured by disruption of mitochondrial transmembrane potential and activation of caspase-9 and -3. betulinic acid 15-29 caspase 9 Homo sapiens 159-175 34374264-9 2021 Conclusion: In the final concentration range of 10 ~ 30 mug/ml, betulinic acid can induce apoptosis of human gastric cancer MGC-803 cells by regulating the expression of Caspase-3, Caspase-9 and Cyt c. betulinic acid 64-78 caspase 9 Homo sapiens 181-190 34234893-6 2021 BA also increased the activity of caspase-9 and -3, and subsequent degradation of the poly (ADP-ribose) polymerase. betulinic acid 0-2 caspase 9 Homo sapiens 34-50 32368052-12 2020 We concluded that one of the important mechanisms of BA-C60(OH)n-GBP-TPGS-NPs inhibiting MHCC97H cells is achieved by up-regulating the expression of Caspase-3, Caspase-8 and Caspase-9. betulinic acid 53-55 caspase 9 Homo sapiens 175-184 34770786-7 2021 Pro-apoptotic markers including Bax, cleaved-caspase-3 and cleaved-caspase-9 were increased while anti-apoptotic marker Bcl-2 was decreased after BA treatment. betulinic acid 146-148 caspase 9 Homo sapiens 67-76 29438593-3 2018 Betulinic acid, thapsigargin, and the calcium ionophore treatment resulted in an increased number of sperm cells with caspase 9 and caspase 3 activation, disrupted mitochondrial membrane potential, and a reacted acrosome. betulinic acid 0-14 caspase 9 Homo sapiens 118-127