PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28274097-6	2017	BA treatment triggered apoptosis by decreasing Bcl-2 levels, activation of capase-3 protease and cleavage of PARP.	betulinic acid	0-2	B cell leukemia/lymphoma 2	Mus musculus	47-52	
21401610-0	2011	Betulinic acid prevention of d-galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms.	betulinic acid	0-14	B cell leukemia/lymphoma 2	Mus musculus	109-114	
21401610-7	2011	We found that BA mediated production of c-jun NH(2) -terminal protein kinase and extracellular signal-regulated kinase induced by D-GalN/LPS, promoted the expression of B-cell CLL/lymphoma 2 (Bcl-2) and restored mitochondrial outer membrane permeabilization.	betulinic acid	14-16	B cell leukemia/lymphoma 2	Mus musculus	169-190	
21401610-7	2011	We found that BA mediated production of c-jun NH(2) -terminal protein kinase and extracellular signal-regulated kinase induced by D-GalN/LPS, promoted the expression of B-cell CLL/lymphoma 2 (Bcl-2) and restored mitochondrial outer membrane permeabilization.	betulinic acid	14-16	B cell leukemia/lymphoma 2	Mus musculus	192-197	
21401610-8	2011	CONCLUSIONS: The results suggested that BA prevented D-GalN/LPS-induced acute liver failure by upregulation of Bcl-2 and antioxidation and mediation of cytokines causing apoptotic cell death and lessened liver damage.	betulinic acid	40-42	B cell leukemia/lymphoma 2	Mus musculus	111-116	
31779213-9	2019	BA also increased the expression of B-cell lymphoma-2 (Bcl-2).	betulinic acid	0-2	B cell leukemia/lymphoma 2	Mus musculus	36-53	
31779213-9	2019	BA also increased the expression of B-cell lymphoma-2 (Bcl-2).	betulinic acid	0-2	B cell leukemia/lymphoma 2	Mus musculus	55-60	
30232032-10	2018	Furthermore, BA treatment increased the expression levels of B-cell lymphoma 2 (Bcl-2), decreased Bcl-2-associated X (Bax), and inhibited the levels of active caspase-3.	betulinic acid	13-15	B cell leukemia/lymphoma 2	Mus musculus	61-78	
30232032-10	2018	Furthermore, BA treatment increased the expression levels of B-cell lymphoma 2 (Bcl-2), decreased Bcl-2-associated X (Bax), and inhibited the levels of active caspase-3.	betulinic acid	13-15	B cell leukemia/lymphoma 2	Mus musculus	80-85	
25959028-4	2015	In addition to reactive oxygen species scavenging activity in Dex-induced splenocytes, BA administration up-regulated antioxidant enzymes, decreased lipid peroxidation, restored mitochondrial function, decreased the expression of pro-apoptotic protein Bax, prevented the decline of anti-apoptotic protein Bcl-2, inhibited caspase-9 and caspase-3 activation, and improved cell survival.	betulinic acid	87-89	B cell leukemia/lymphoma 2	Mus musculus	305-310	
26721359-7	2016	In addition to ROS scavenging activity in Dex-induced thymocyte, BA administration decreased lipid peroxidation, up-regulated antioxidant enzymes, restored mitochondrial function, increased Bcl-2 expression but reduced Bax expression, inhibited caspase-3 activation, and improved cell survival.	betulinic acid	65-67	B cell leukemia/lymphoma 2	Mus musculus	190-195