PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33806566-7	2021	BA up-regulated the expression of Bcl-2-accociated X protein (Bax) and cleaved poly-ADP ribose polymerase (PARP), and subsequently activated caspase-3, -8, and -9.	betulinic acid	0-2	poly(ADP-ribose) polymerase 1	Homo sapiens	79-105	
33806566-7	2021	BA up-regulated the expression of Bcl-2-accociated X protein (Bax) and cleaved poly-ADP ribose polymerase (PARP), and subsequently activated caspase-3, -8, and -9.	betulinic acid	0-2	poly(ADP-ribose) polymerase 1	Homo sapiens	107-111	
28208611-6	2017	Inhibition of cell survival by BA at 10 and 20 microM concentrations occurred as a result of alteration in Bax/Bcl-2 ratio in both cell lines that led to an increased cytochrome C release, caspase activation and poly(ADP)ribose polymerase (PARP) cleavage, leading to apoptosis.	betulinic acid	31-33	poly(ADP-ribose) polymerase 1	Homo sapiens	240-244	
25361208-6	2014	Incubation using both BA derivatives led to decreased cell migration, cleavage of PARP and decreased protein expression levels of Survivin.	betulinic acid	22-24	poly(ADP-ribose) polymerase 1	Homo sapiens	82-86	
10336521-4	1999	BA-induced apoptosis involves the activation of caspases that cleave poly(ADP ribose)polymerase.	betulinic acid	0-2	poly(ADP-ribose) polymerase 1	Homo sapiens	69-95	
34234893-6	2021	BA also increased the activity of caspase-9 and -3, and subsequent degradation of the poly (ADP-ribose) polymerase.	betulinic acid	0-2	poly(ADP-ribose) polymerase 1	Homo sapiens	86-114