PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17363604-3	2007	Using LNCaP prostate cancer cells as a model, we now show that betulinic acid decreases expression of vascular endothelial growth (VEGF) and the antiapoptotic protein survivin.	betulinic acid	63-77	vascular endothelial growth factor A	Homo sapiens	131-135	
17363604-4	2007	The mechanism of these betulinic acid-induced antiangiogenic and proapoptotic responses in both LNCaP cells and in tumors is due to activation of selective proteasome-dependent degradation of the transcription factors specificity protein 1 (Sp1), Sp3, and Sp4, which regulate VEGF and survivin expression.	betulinic acid	23-37	vascular endothelial growth factor A	Homo sapiens	276-280	
31948750-5	2020	We found that BA inhibited the hypoxia-induced accumulation of HIF-1alpha without affecting HIF-1alpha mRNA levels and suppressed the expression of HIF target genes, including VEGF, GLUT1, and PDK1 in HeLa cells.	betulinic acid	14-16	vascular endothelial growth factor A	Homo sapiens	176-180	
21731766-5	2011	In addition, BA significantly reduced cellular and secreted levels of vascular endothelial growth factor (VEGF), a critical angiogenic factor and a target gene of STAT3 induced under hypoxia.	betulinic acid	13-15	vascular endothelial growth factor A	Homo sapiens	70-104	
21731766-5	2011	In addition, BA significantly reduced cellular and secreted levels of vascular endothelial growth factor (VEGF), a critical angiogenic factor and a target gene of STAT3 induced under hypoxia.	betulinic acid	13-15	vascular endothelial growth factor A	Homo sapiens	106-110	
21731766-7	2011	Of note, chromatin immunoprecipitation (ChiP) assay revealed that BA inhibited binding of HIF-1alpha and STAT3 to VEGF promoter.	betulinic acid	66-68	vascular endothelial growth factor A	Homo sapiens	114-118	
20174965-0	2010	Betulinic acid inhibits the expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor in human endometrial adenocarcinoma cells.	betulinic acid	0-14	vascular endothelial growth factor A	Homo sapiens	78-112