PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33374365-11 2020 In addition, BA treatment significantly reduced DOX-induced cell apoptosis and protein expression levels of Bax and cleaved caspase-3/-9, while the expression of Bcl-2 was increased by BA. betulinic acid 13-15 caspase 3 Rattus norvegicus 124-136 30125567-6 2018 The H/R-mediated changes in caspase-3 activity and expressions of Bax and Bcl-2 were restored by betulinic acid treatment. betulinic acid 97-111 caspase 3 Rattus norvegicus 28-37 27876208-6 2016 Furthermore, the down-regulation of Bcl-2, up-regulation of Bax and the consequent activation of caspase-3 induced by OGD/R were reversed by BA pretreatment. betulinic acid 141-143 caspase 3 Rattus norvegicus 97-106 18704645-16 2008 Similar response was obtained with betulinic acid and thapsigargin (TPS) on caspase-3 activity compared to basal. betulinic acid 35-49 caspase 3 Rattus norvegicus 76-85