PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30594361-10 2019 However, in response to simultaneous interference of INSIG1 and INSIG2, the marked increase in content of TAG and TC and accumulation of lipids along with significant upregulation of SREBF1, ACACA, SCD1, AGPAT6, and DGAT2 suggested that INSIG1 and INSIG2 synergistically regulate milk fat synthesis in GMEC. gmec 302-306 insulin-induced gene 1 protein Capra hircus 53-59