PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17929017-3	2008	In this study, we selected three structurally different histone deacetylase (HDAC) inhibitors, apicidin, MS275, and sodium butyrate that activate p38, to probe the signal pathway from activin A to p38 in chronic myeloid leukemia (CML)-derived K562 cells.	apicidin	95-103	mitogen-activated protein kinase 14	Homo sapiens	146-149	
17910885-0	2007	Mechanisms of human gamma-globin transcriptional induction by apicidin involves p38 signaling to chromatin.	apicidin	62-70	mitogen-activated protein kinase 14	Homo sapiens	80-83	
17910885-2	2007	The HDAC inhibitor apicidin was recently reported as a powerful inducer of HbF via a mechanism involving p38 signaling.	apicidin	19-27	mitogen-activated protein kinase 14	Homo sapiens	105-108	
17910885-6	2007	Inhibition of p38 signaling blocks the effects of apicidin-induced gamma-globin expression and H3 acetylation.	apicidin	50-58	mitogen-activated protein kinase 14	Homo sapiens	14-17	
17910885-10	2007	Collectively, our results provide a molecular basis to elucidate the underlying mechanisms involving p38 signaling pathway in the inducement of gamma-globin transcriptional expression by apicidin.	apicidin	187-195	mitogen-activated protein kinase 14	Homo sapiens	101-104	
12393499-5	2003	Furthermore, analysis of different mitogen-activated protein (MAP) kinase signaling pathways revealed that p38 signaling was activated following apicidin treatment of cells and that inhibition of this pathway abolished the HbF-inducing effect of apicidin.	apicidin	145-153	mitogen-activated protein kinase 14	Homo sapiens	107-110	
12393499-5	2003	Furthermore, analysis of different mitogen-activated protein (MAP) kinase signaling pathways revealed that p38 signaling was activated following apicidin treatment of cells and that inhibition of this pathway abolished the HbF-inducing effect of apicidin.	apicidin	246-254	mitogen-activated protein kinase 14	Homo sapiens	107-110	
12393499-6	2003	Additionally, activation of the Agamma-globin promoter by apicidin could be inhibited by p38 inhibitor SB203580.	apicidin	58-66	mitogen-activated protein kinase 14	Homo sapiens	89-92