PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17258775-4 2007 It was demonstrated that apicidin and n-butyrate induced a continuous acetylation of histones H4 and H3, inhibited the proliferation of EoL-1 cells without attenuating the level of FIP1L1-PDGFRA mRNA, and induced the expression of markers for mature eosinophils such as integrin beta7, CCR1, and CCR3 on EoL-1 cells, while trichostatin A evoked a transient acetylation of histones and induced no differentiation into eosinophils. apicidin 25-33 platelet derived growth factor receptor alpha Homo sapiens 188-194 18504399-3 2008 The HDAC inhibitors apicidin and n-butyrate suppress the proliferation of EoL-1 cells and induce differentiation into eosinophils by a decrease in the protein level of FIP1L1-PDGFRalpha without affecting the mRNA level for FIP1L1-PDGFRA. apicidin 20-28 platelet derived growth factor receptor alpha Homo sapiens 230-236