PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29185103-14 2017 Aspirin, ticagrelor, and rosuvastatin all decreased TNF-alpha levels. Rosuvastatin Calcium 25-37 tumor necrosis factor Mus musculus 52-61 30822620-0 2019 Beneficial anti-inflammatory effects of combined rosuvastatin and cilostazol in a TNF-driven inflammatory model. Rosuvastatin Calcium 49-61 tumor necrosis factor Mus musculus 82-85 30822620-8 2019 RESULTS: Compared to the treatment with cilostazol alone, the combination treatment with rosuvastatin and cilostazol significantly reduced not only the levels of TNF in the sera but also macrophage infiltration in aortic lesions. Rosuvastatin Calcium 89-101 tumor necrosis factor Mus musculus 162-165 30822620-10 2019 CONCLUSION: Rosuvastatin combined with cilostazol therapy can greatly improve the anti-inflammatory effect of monotherapies, resulting in reduced mortality of mice; thus, we propose the potential of use of this combination therapy as anti-TNF agent. Rosuvastatin Calcium 12-24 tumor necrosis factor Mus musculus 239-242 16685407-9 2006 Rosuvastatin also inhibited increases in intestinal TNF-alpha protein and mRNA expression after DSS administration, respectively. Rosuvastatin Calcium 0-12 tumor necrosis factor Mus musculus 52-61 28025996-11 2016 Rosuvastatin significantly decreased the expression levels of pro-inflammatry cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-6 and transforming growth factor (TGF)-beta1. Rosuvastatin Calcium 0-12 tumor necrosis factor Mus musculus 97-130 22382902-13 2012 Furthermore, treatment with rosuvastatin decreased the expression levels of TNF-alpha (group H, 65.19 +- 7.06 pg/ml; group L, 108.20 +- 5.28 pg/ml; group N, 239.34 +- 11.65 pg/ml) and IL-6 (group H, 14.33 +- 2.15 pg/ml; group L, 19.67 +- 3.04 pg/ml; group N, 40.39 +- 7.17 pg/ml). Rosuvastatin Calcium 28-40 tumor necrosis factor Mus musculus 76-85 27316397-7 2016 CONCLUSION: AS attenuated progression of atherosclerosis lesion formation alone or combined with rosuvastatin through anti-inflammatory effect, resulting in down-regulation of TNF-alpha and IL-6, and further down-regulating IL-8 and MCP-1 expressions in aorta of WD fed ApoE(-/-) mice. Rosuvastatin Calcium 97-109 tumor necrosis factor Mus musculus 176-185 23107893-7 2012 MCP-1 mRNA level was significantly increased in injured femoral arteries, and administration of irbesartan with rosuvastatin decreased the mRNA levels of MCP-1, TNFalpha, and IL-1beta, and increased PPARgamma mRNA expression. Rosuvastatin Calcium 112-124 tumor necrosis factor Mus musculus 161-169 22613653-11 2012 RESULTS: Rosuvastatin reduced the number of total inflammatory cells, lymphocytes, macrophages, neutrophils, and eosinophils recruited into BALF, the levels of IL-4, IL-5, IL-13 and TNF-alpha in BALF, along with the histological mucus index (HMI) and GABAAR beta2 expression. Rosuvastatin Calcium 9-21 tumor necrosis factor Mus musculus 182-191 12939225-9 2003 Furthermore, rosuvastatin specifically suppressed the expression of the inflammation parameters MCP-1 and TNF-alpha in the vessel wall and lowered plasma concentrations of serum amyloid A and fibrinogen, independent of its cholesterol-lowering effect. Rosuvastatin Calcium 13-25 tumor necrosis factor Mus musculus 106-115