PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1424138-0 1992 Effect of pyridoxal 5-phosphate on the stability of alanine aminotransferase. Pyridoxal Phosphate 10-31 glutamic--pyruvic transaminase Homo sapiens 52-76 8831054-2 1996 Pyridoxal-5"-phosphate caused an increase of 1 to 20 U/l in aspartate aminotransferase and alanine aminotransferase activity in 90 and 78 patient plasma samples, respectively. Pyridoxal Phosphate 0-22 glutamic--pyruvic transaminase Homo sapiens 91-115 6733898-0 1984 Comparison of pyridoxal phosphate-supplemented reagent kits for alanine aminotransferase using centrifugal analysis. Pyridoxal Phosphate 14-33 glutamic--pyruvic transaminase Homo sapiens 64-88 2596431-8 1989 3) Inorganic phosphate inhibits in vitro activation of E-GPT by pyridoxal-5"-phosphate. Pyridoxal Phosphate 64-86 glutamic--pyruvic transaminase Homo sapiens 57-60 4067514-3 1985 The stimulation in vitro of the activities of aspartate aminotransferase and alanine aminotransferase by addition of pyridoxal 5"-phosphate (0.1 mmol/l) was found to be independent of the endogenous coenzyme level. Pyridoxal Phosphate 117-139 glutamic--pyruvic transaminase Homo sapiens 77-101 1931970-7 1991 All of the crucial amino acid residues are conserved in human GPT, which seem to be hydrogen bonding to pyridoxal 5"-phosphate in rat GPT by the sequence homology to other alpha-aminotransferases with known tertiary structures. Pyridoxal Phosphate 104-126 glutamic--pyruvic transaminase Homo sapiens 62-65 3577954-2 1987 It was found that ASAT and ALAT mean values were significantly higher in both groups in the presence of P5P, than in the absence of P5P. Pyridoxal Phosphate 104-107 glutamic--pyruvic transaminase Homo sapiens 27-31 3577954-2 1987 It was found that ASAT and ALAT mean values were significantly higher in both groups in the presence of P5P, than in the absence of P5P. Pyridoxal Phosphate 132-135 glutamic--pyruvic transaminase Homo sapiens 27-31 6733898-1 1984 The addition of pyridoxal-5-phosphate for assay of alanine aminotransferase has been recommended. Pyridoxal Phosphate 16-37 glutamic--pyruvic transaminase Homo sapiens 51-75 6698365-3 1984 Addition of pyridoxal phosphate to liver homogenates increased liver alanine aminotransferase, but not aspartate aminotransferase, in all patients with initially low plasma pyridoxal phosphate. Pyridoxal Phosphate 12-31 glutamic--pyruvic transaminase Homo sapiens 69-93 7026088-0 1981 On the pyridoxal-5"-phosphate stimulation of aspartate aminotransferase and alanine aminotransferase in serum and erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants. Pyridoxal Phosphate 7-29 glutamic--pyruvic transaminase Homo sapiens 76-100 7039870-0 1982 [In vitro supplementation of pyridoxal phosphate for the optimisation of the determination of the catalytic activity of alanine aminotransferase and aspartate aminotransferase in kidney transplant patients (author"s transl)]. Pyridoxal Phosphate 29-48 glutamic--pyruvic transaminase Homo sapiens 120-144 7039870-1 1982 Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Pyridoxal Phosphate 0-19 glutamic--pyruvic transaminase Homo sapiens 45-69 7039870-1 1982 Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST). Pyridoxal Phosphate 21-24 glutamic--pyruvic transaminase Homo sapiens 45-69 6616834-3 1983 The concentration of pyridoxal 5"-phosphate in plasma at the time the patients entered the hospital correlated significantly with their activities of serum alanine aminotransferase. Pyridoxal Phosphate 21-43 glutamic--pyruvic transaminase Homo sapiens 156-180 7447458-0 1980 Depletion of cultured human fibroblasts of pyridoxal 5"-phosphate: effect on activities of aspartate aminotransferase, alanine aminotransferase, and cystathionine beta-synthase. Pyridoxal Phosphate 43-65 glutamic--pyruvic transaminase Homo sapiens 119-143 1183047-0 1975 Effect of pyridoxal 5"-phosphate on the temperature relationships of alanine aminotransferase. Pyridoxal Phosphate 10-32 glutamic--pyruvic transaminase Homo sapiens 69-93 7378307-3 1980 This activity could be restored by in vitro incubation with pyridoxal phosphate suggesting that the effect was due to low levels of B6 rather than to a primary abnormality of the GPT. Pyridoxal Phosphate 60-79 glutamic--pyruvic transaminase Homo sapiens 179-182 894196-0 1977 Pyridoxal 5"-phosphate as an activator of the apoenzyme of alanine aminotransferase in human serum. Pyridoxal Phosphate 0-22 glutamic--pyruvic transaminase Homo sapiens 59-83 894196-1 1977 The relationship between reaction conditions and the stimulation of alanine aminotransferase by pyridoxal 5"-phosphate was investigated. Pyridoxal Phosphate 96-118 glutamic--pyruvic transaminase Homo sapiens 68-92 894196-2 1977 Reaction conditions given for optimized alanine aminotransferase measurements are also optimal for measurements in the presence of pyridoxal 5"-phosphate taking into consideration the inhibitory effect of phosphate buffer. Pyridoxal Phosphate 131-153 glutamic--pyruvic transaminase Homo sapiens 40-64 832380-3 1977 Preincubation of 22 normal sera, in a 10:1 ratio with an 8.09 mmol/liter pyridoxal phosphate solution, resulted in an increase in the alanine aminotransferase activity from 10.5 +/- 4.9 U/liter (mean +/- SD) to 28.4 +/- 5.3 U/liter, an increase of 170%. Pyridoxal Phosphate 73-92 glutamic--pyruvic transaminase Homo sapiens 134-158 438731-0 1979 Influence of pyridoxal-5"-phosphate on the determination of the alanine aminotransferase and aspartate aminotransferase of commercial test sera. Pyridoxal Phosphate 13-35 glutamic--pyruvic transaminase Homo sapiens 64-88 719898-1 1978 In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons. Pyridoxal Phosphate 43-65 glutamic--pyruvic transaminase Homo sapiens 150-174 719898-1 1978 In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons. Pyridoxal Phosphate 67-72 glutamic--pyruvic transaminase Homo sapiens 150-174 337888-3 1977 Aspartate aminotransferase and alanine aminotransferase require pyridoxal phosphate for expression of enzyme activity. Pyridoxal Phosphate 64-83 glutamic--pyruvic transaminase Homo sapiens 31-55 832380-0 1977 Activation of alanine aminotransferase in serum by pyridoxal phosphate. Pyridoxal Phosphate 51-70 glutamic--pyruvic transaminase Homo sapiens 14-38 832380-1 1977 Alanine aminotransferase activity in serum increases significantly when serum is incubated with pyridoxal phosphate. Pyridoxal Phosphate 96-115 glutamic--pyruvic transaminase Homo sapiens 0-24 241701-5 1975 Red cell GPT of all the 3 common phenotypes in both adults and children was found to show a similar response to the addition of excess pyridoxal phosphate. Pyridoxal Phosphate 135-154 glutamic--pyruvic transaminase Homo sapiens 9-12 11330835-2 2001 In this study, the authors have demonstrated for the first time an inhibitory effect of in vitro glycation on the catalytic activity of alanine aminotransferase (ALT, EC 2.6.1.2), a pyridoxal phosphate enzyme with several lysine residues in the molecule. Pyridoxal Phosphate 182-201 glutamic--pyruvic transaminase Homo sapiens 136-160