PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27784725-3 2017 A central SL signaling molecule is sphingosine-1-phosphate (S1P), whose breakdown is catalyzed by S1P lyase (S1PL), a pyridoxal 5"-phosphate (PLP)-dependent enzyme that catalyzes the cleavage of S1P to (2E)-hexadecenal (2E-HEX) and phosphoethanolamine. Pyridoxal Phosphate 118-140 hematopoietically expressed homeobox Homo sapiens 223-226 27784725-3 2017 A central SL signaling molecule is sphingosine-1-phosphate (S1P), whose breakdown is catalyzed by S1P lyase (S1PL), a pyridoxal 5"-phosphate (PLP)-dependent enzyme that catalyzes the cleavage of S1P to (2E)-hexadecenal (2E-HEX) and phosphoethanolamine. Pyridoxal Phosphate 142-145 hematopoietically expressed homeobox Homo sapiens 223-226