PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
2138001-2	1990	Measurement of elevated serum AST activity is dependent upon the inclusion of pyridoxal 5-phosphate in the substrate.	Pyridoxal Phosphate	78-99	solute carrier family 17 member 5	Homo sapiens	30-33	
35061954-9	2022	The mean deviations for the non-P-5"-P AST group were reduced remarkably (-3.0% to 3.3%).Conclusion: Assays supplemented with P-5"-P exhibited poor performance against RMP for both ALT and AST.	Pyridoxal Phosphate	126-132	solute carrier family 17 member 5	Homo sapiens	39-42	
35061954-9	2022	The mean deviations for the non-P-5"-P AST group were reduced remarkably (-3.0% to 3.3%).Conclusion: Assays supplemented with P-5"-P exhibited poor performance against RMP for both ALT and AST.	Pyridoxal Phosphate	126-132	solute carrier family 17 member 5	Homo sapiens	189-192	
3233744-1	1988	Serum aspartate aminotransferase (AST) activity was measured by the methods recommended by the Scandinavian Committee on Enzymes (SCE) and by the International Federation of Clinical Chemistry (IFCC) with pyridoxal phosphate (PLP) and without (-PLP) in one laboratory at 37 degrees C with the Abbott ABA-100 and in another at 30 degrees C with the IL Multistat III.	Pyridoxal Phosphate	205-224	solute carrier family 17 member 5	Homo sapiens	34-37	
3600038-5	1987	The presence of macro-AST can be determined by exclusion chromatography, electrophoresis, and activation assays with pyridoxal 5-phosphate.	Pyridoxal Phosphate	117-138	solute carrier family 17 member 5	Homo sapiens	22-25	
3772227-3	1986	We found that these enzymes were stable for catalytic activity and immunologic (mass) measurements up to 24 hours at ambient temperatures and for at least 28 days at 4 degrees, -20 degrees, and -80 degrees C. The addition of exogenous pyridoxal phosphate (0.1 mmol/L) to serum improved stability of AST storage at ambient temperature (22 degrees C) from 1 day to 7 days.	Pyridoxal Phosphate	235-254	solute carrier family 17 member 5	Homo sapiens	299-302	
3008634-1	1986	In vitro supplementation with the active form of vitamin B6, pyridoxal-phosphate (PLP), increases measurements of both serum aminotransferase enzymes, L-aspartate: 2-oxoglutarate amino transferase, EC 2.6.1.1 (AST) and L-alanine: 2-oxoglutarate aminotransferase, EC 2.6.1.2 (ALT).	Pyridoxal Phosphate	61-80	solute carrier family 17 member 5	Homo sapiens	210-213	
7039870-0	1982	[In vitro supplementation of pyridoxal phosphate for the optimisation of the determination of the catalytic activity of alanine aminotransferase and aspartate aminotransferase in kidney transplant patients (author"s transl)].	Pyridoxal Phosphate	29-48	solute carrier family 17 member 5	Homo sapiens	149-175	
7039870-1	1982	Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).	Pyridoxal Phosphate	0-19	solute carrier family 17 member 5	Homo sapiens	80-106	
7039870-1	1982	Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).	Pyridoxal Phosphate	0-19	solute carrier family 17 member 5	Homo sapiens	108-111	
7039870-1	1982	Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).	Pyridoxal Phosphate	21-24	solute carrier family 17 member 5	Homo sapiens	80-106	
7039870-1	1982	Pyridoxal phosphate (PLP) is the coenzyme of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).	Pyridoxal Phosphate	21-24	solute carrier family 17 member 5	Homo sapiens	108-111	
7026088-0	1981	On the pyridoxal-5"-phosphate stimulation of aspartate aminotransferase and alanine aminotransferase in serum and erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants.	Pyridoxal Phosphate	7-29	solute carrier family 17 member 5	Homo sapiens	45-71	
7026088-1	1981	Aspartate aminotransferase (AST) determinations in erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants showed that patients receiving vitamin B6 had a smaller relative stimulation rate of AST by pyridoxal-5"-phosphate (P-5-P).	Pyridoxal Phosphate	229-251	solute carrier family 17 member 5	Homo sapiens	0-26	
7026088-1	1981	Aspartate aminotransferase (AST) determinations in erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants showed that patients receiving vitamin B6 had a smaller relative stimulation rate of AST by pyridoxal-5"-phosphate (P-5-P).	Pyridoxal Phosphate	229-251	solute carrier family 17 member 5	Homo sapiens	222-225	
7026088-1	1981	Aspartate aminotransferase (AST) determinations in erythrocytes of patients undergoing chronic haemodialysis and with kidney transplants showed that patients receiving vitamin B6 had a smaller relative stimulation rate of AST by pyridoxal-5"-phosphate (P-5-P).	Pyridoxal Phosphate	253-258	solute carrier family 17 member 5	Homo sapiens	0-26	
7026088-3	1981	The corresponding relative stimulation rates of AST and ALT by P-5-P addition to the reaction mixture were not changed in the haemodialysis patients, but in renal transplant recipients the relative stimulation rate of AST was significantly smaller and that of ALT was greater.	Pyridoxal Phosphate	63-68	solute carrier family 17 member 5	Homo sapiens	48-51	
719898-1	1978	In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons.	Pyridoxal Phosphate	43-65	solute carrier family 17 member 5	Homo sapiens	75-101	
719898-1	1978	In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons.	Pyridoxal Phosphate	43-65	solute carrier family 17 member 5	Homo sapiens	103-106	
719898-1	1978	In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons.	Pyridoxal Phosphate	67-72	solute carrier family 17 member 5	Homo sapiens	75-101	
719898-1	1978	In activity determination with addition of pyridoxal 5"-phosphate (P-5-P), aspartate aminotransferase (AST) activity increases by 6.5 U/l and that of alanine aminotransferase (ALT) by 2.5 U/l in the serum of healthy persons.	Pyridoxal Phosphate	67-72	solute carrier family 17 member 5	Homo sapiens	103-106	
30289764-5	2018	AST elevations tend to be higher than ALT elevations; the reason is ascribed to hepatic deficiency of pyridoxal 5"-phosphate, a cofactor of the enzymatic activity of ALT, which leads to a lesser increase in ALT than in AST.	Pyridoxal Phosphate	102-124	solute carrier family 17 member 5	Homo sapiens	0-3	
30289764-5	2018	AST elevations tend to be higher than ALT elevations; the reason is ascribed to hepatic deficiency of pyridoxal 5"-phosphate, a cofactor of the enzymatic activity of ALT, which leads to a lesser increase in ALT than in AST.	Pyridoxal Phosphate	102-124	solute carrier family 17 member 5	Homo sapiens	219-222