PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34856074-6 2022 We demonstrate that SRC is activated in response to treatment of KRAS-mutant colorectal cell lines with MEK inhibitors (trametinib or AZD6244), and that AZD0424 abrogates this. AZD 6244 134-141 Rous sarcoma oncogene Mus musculus 20-23 32876513-7 2021 The IGF2BP1-SRC/ERK2 axis is targetable by the SRC-inhibitor saracatinib and MEK-inhibitor selumetinib. AZD 6244 91-102 Rous sarcoma oncogene Mus musculus 12-15 34856074-7 2022 Cell lines treated with trametinib or AZD6244 in combination with AZD0424 had reduced EGFR, FAK and SRC compensatory activation, and, cell viability was synergistically inhibited. AZD 6244 38-45 Rous sarcoma oncogene Mus musculus 100-103