PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26567773-8 2015 Moreover, the anti-angiogenesis effect of AZD6244 may predominantly attribute to its modulation on VEGF through p-ERK - c-Fos - HIF-1alpha integrated signal pathways. AZD 6244 42-49 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 120-125 26567773-11 2015 The anti-angiogenesis effect afford by AZD6244 may attribute to its modulation on p-ERK - c-Fos - HIF-1alpha - VEGF integrated signal pathways. AZD 6244 39-46 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 90-95 17854307-7 2007 In addition to ERK inhibition, NFATc1 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1) and c-fos were both downregulated, suggesting that AZD6244 targets a later stage of OCL differentiation. AZD 6244 165-172 Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens 118-123