PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24378685-6 2014 CAPE significantly and dose-dependently reduced LPS-induced nitrite production, as well as the transcription and protein synthesis of monocyte chemoattractant protein-1 (MCP-1), interleukin-6 (IL-6) and inducible nitric oxide synthase (iNOS), as determined by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), western blotting and enzyme-linked immunosorbent assays (ELISA). caffeic acid phenethyl ester 0-4 interleukin 6 Rattus norvegicus 178-191 24378685-6 2014 CAPE significantly and dose-dependently reduced LPS-induced nitrite production, as well as the transcription and protein synthesis of monocyte chemoattractant protein-1 (MCP-1), interleukin-6 (IL-6) and inducible nitric oxide synthase (iNOS), as determined by quantitative reverse transcription-polymerase chain reaction (qRT-PCR), western blotting and enzyme-linked immunosorbent assays (ELISA). caffeic acid phenethyl ester 0-4 interleukin 6 Rattus norvegicus 193-197 16983503-4 2006 The levels of tumor necrosis factor-alpha, interleukin-6, and interleukin-1alpha in the caffeic acid phenethyl ester group were significantly lower than those in the bile duct ligation group (P < 0.03, P < 0.01, and P < 0.02 respectively). caffeic acid phenethyl ester 88-116 interleukin 6 Rattus norvegicus 43-56 19535096-8 2010 In CAPE treated group, the levels of interleukin-1alpha (IL-1alpha) and interleukin-6 (IL-6) were significantly lower than that of BDL group (P < 0.03, P < 0.02, respectively). caffeic acid phenethyl ester 3-7 interleukin 6 Rattus norvegicus 72-85 19535096-8 2010 In CAPE treated group, the levels of interleukin-1alpha (IL-1alpha) and interleukin-6 (IL-6) were significantly lower than that of BDL group (P < 0.03, P < 0.02, respectively). caffeic acid phenethyl ester 3-7 interleukin 6 Rattus norvegicus 87-91 34754212-8 2021 More interestingly, the one-way ANOVA data demonstrated a decreased level of proinflammatory IL-6 in the CAPE-treated group compared to the negative control. caffeic acid phenethyl ester 105-109 interleukin 6 Rattus norvegicus 93-97 14751512-9 2004 CAPE treatment inhibited the radiation-induced expression of IL-6, IL-6 receptors (IL-6rs), and SOCS3 at 3 days. caffeic acid phenethyl ester 0-4 interleukin 6 Rattus norvegicus 61-65 14751512-9 2004 CAPE treatment inhibited the radiation-induced expression of IL-6, IL-6 receptors (IL-6rs), and SOCS3 at 3 days. caffeic acid phenethyl ester 0-4 interleukin 6 Rattus norvegicus 67-71 31059064-5 2019 In addition, CAPE decreased the severity of inflammation in the retina, reflected by the decreased expression of inflammatory cytokines, including interleukin (IL)-8, IL-6, inducible nitric oxide synthase, cycloooxygenase-2, tumor necrosis factor-alpha and chemokine C-C ligand-2, in CAPE-treated rats. caffeic acid phenethyl ester 13-17 interleukin 6 Rattus norvegicus 167-171 26044239-7 2015 RESULTS: In CAPE treated group, decreased serum levels of proinflammatory cytokines (TNF-alpha, IL-6, IL-1beta) and CRP (p < 0.05), additionally increased serum levels of antioxidant parameters (PONS, TAS) (p < 0.05), were observed after IO. caffeic acid phenethyl ester 12-16 interleukin 6 Rattus norvegicus 96-100 30192364-0 2018 Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF-&alpha; Levels and Local Inflammatory Responses in Spinal Cord Injuries. caffeic acid phenethyl ester 23-51 interleukin 6 Rattus norvegicus 62-66 30192364-0 2018 Effects of Intrathecal Caffeic Acid Phenethyl Ester (CAPE) on IL-6 and TNF-&alpha; Levels and Local Inflammatory Responses in Spinal Cord Injuries. caffeic acid phenethyl ester 53-57 interleukin 6 Rattus norvegicus 62-66 30192364-1 2018 AIM: To investigate the effects of intrathecal caffeic acid phenethyl ester (CAPE) on tissue and serum interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-?) levels following spinal cord injury (SCI) as well as its effects on edema and microhemorrhage. caffeic acid phenethyl ester 47-75 interleukin 6 Rattus norvegicus 103-116 30192364-1 2018 AIM: To investigate the effects of intrathecal caffeic acid phenethyl ester (CAPE) on tissue and serum interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-?) levels following spinal cord injury (SCI) as well as its effects on edema and microhemorrhage. caffeic acid phenethyl ester 77-81 interleukin 6 Rattus norvegicus 103-116 30192364-1 2018 AIM: To investigate the effects of intrathecal caffeic acid phenethyl ester (CAPE) on tissue and serum interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-?) levels following spinal cord injury (SCI) as well as its effects on edema and microhemorrhage. caffeic acid phenethyl ester 77-81 interleukin 6 Rattus norvegicus 118-122 30192364-9 2018 RESULTS: The decrease in IL-6 levels in the CAPE group was significantly higher than that in the sham and control groups. caffeic acid phenethyl ester 44-48 interleukin 6 Rattus norvegicus 25-29 30192364-14 2018 CONCLUSION: Intrathecal CAPE administration following SCI decreases tissue and serum IL-6 levels as well as decreases spinal cord edema and microhemorrhage. caffeic acid phenethyl ester 24-28 interleukin 6 Rattus norvegicus 85-89