PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30552692-8 2019 Furthermore, salidroside blocked the PDGF-induced activation of the nuclear factor-kappaB (NF-kappaB) pathway in ASMCs. rhodioloside 13-24 nuclear factor kappa B subunit 1 Homo sapiens 68-89 33749640-0 2021 Salidroside induces cell apoptosis and inhibits the invasiveness of HT29 colorectal cells by regulating protein kinase R, NF-kappaB and STAT3. rhodioloside 0-11 nuclear factor kappa B subunit 1 Homo sapiens 122-131 31747547-0 2020 Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-kappaB/NLRP3 signaling pathway in AGEs-induced HUVECs. rhodioloside 0-11 nuclear factor kappa B subunit 1 Homo sapiens 93-102 31747547-13 2020 Our findings suggest that salidroside ameliorates AGEs-induced endothelial inflammation and oxidative stress, partially via the AMPK/NF-kappaB/NLRP3 signaling pathway. rhodioloside 26-37 nuclear factor kappa B subunit 1 Homo sapiens 133-142 30552692-8 2019 Furthermore, salidroside blocked the PDGF-induced activation of the nuclear factor-kappaB (NF-kappaB) pathway in ASMCs. rhodioloside 13-24 nuclear factor kappa B subunit 1 Homo sapiens 91-100 30552692-9 2019 The results suggested that salidroside functionally regulated the proliferation, migration, phenotype plasticity, and extracellular matrix deposition in PDGF-induced ASMCs and the NF-kappaB pathway might be implicated in the effects of salidroside on ASMCs induced by PDGF. rhodioloside 236-247 nuclear factor kappa B subunit 1 Homo sapiens 180-189 29679467-7 2018 We also showed that nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/heme oxygenase 1 (HO-1) and nuclear factor kappa B (NF-kappaB) signaling was critical for the salidroside-mediated beneficial regulation. rhodioloside 165-176 nuclear factor kappa B subunit 1 Homo sapiens 99-121 30944705-0 2019 Salidroside regulates the expressions of IL-6 and defensins in LPS-activated intestinal epithelial cells through NF-kappaB/MAPK and STAT3 pathways. rhodioloside 0-11 nuclear factor kappa B subunit 1 Homo sapiens 113-122 30944705-7 2019 Western blot results showed that salidroside repressed the phosphorylation of NF-kB, Erk1/2, JNK, P38, JAK2 and STAT3 (P<0.05) and attenuated the activation of NF-kappaB, MAPK, and STAT3 pathways. rhodioloside 33-44 nuclear factor kappa B subunit 1 Homo sapiens 163-172 30944705-9 2019 Conclusion: In summary, salidroside suppressed the expression of IL-6 and elevated the expression of defensins in LPS-activated intestinal epithelial cells through NF-kappaB/MAPK and STAT3 pathways. rhodioloside 24-35 nuclear factor kappa B subunit 1 Homo sapiens 164-173 29679467-7 2018 We also showed that nuclear factor (erythroid-derived 2)-like 2 (Nrf2)/heme oxygenase 1 (HO-1) and nuclear factor kappa B (NF-kappaB) signaling was critical for the salidroside-mediated beneficial regulation. rhodioloside 165-176 nuclear factor kappa B subunit 1 Homo sapiens 123-132 29679467-8 2018 CONCLUSIONS Our results demonstrate that salidroside protects against AGE-induced endothelial dysfunction, and its effects may be in part attributed to the induction of HO-1 and attenuation of phosphorylated NF-kappaB p65. rhodioloside 41-52 nuclear factor kappa B subunit 1 Homo sapiens 208-217 25341565-0 2014 Salidroside attenuates allergic airway inflammation through negative regulation of nuclear factor-kappa B and p38 mitogen-activated protein kinase. rhodioloside 0-11 nuclear factor kappa B subunit 1 Homo sapiens 83-105 26241782-0 2015 Protective activity of salidroside against ethanol-induced gastric ulcer via the MAPK/NF-kappaB pathway in vivo and in vitro. rhodioloside 23-34 nuclear factor kappa B subunit 1 Homo sapiens 86-95 26241782-9 2015 Collectively, it is assumed that Sal could alleviate ethanol-induced acute gastric ulcer and H2O2-induced gastric epithelial cell damage through the MAPK/NF-kappaB pathway. rhodioloside 33-36 nuclear factor kappa B subunit 1 Homo sapiens 154-163 24180550-6 2013 In addition, we further investigated signal transduction mechanisms and found that the activation of NF-kappaB was suppressed by salidroside in a dose-dependent manner. rhodioloside 129-140 nuclear factor kappa B subunit 1 Homo sapiens 101-110 24180550-7 2013 These results suggest that salidroside suppresses NO and PGE2 production by inhibiting iNOS and COX-2 protein expression, level of [Ca2+](i), and activation of NF-kappaB signal transduction pathway. rhodioloside 27-38 nuclear factor kappa B subunit 1 Homo sapiens 160-169