PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34467560-11	2022	CONCLUSION: Salidroside exerts protective effect against diabetes-induced cardiac dysfunction by modulating the mTOR and AMPK signaling pathways.	rhodioloside	12-23	mechanistic target of rapamycin kinase	Rattus norvegicus	112-116	
24989011-5	2014	Moreover, phosphorylated mammalian target of rapamycin (p-mTOR) was significantly reduced by CoCl2, and this inhibition was relieved by the treatment of SA in PC12 cells, as evidenced by immunoblot and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analyses.	rhodioloside	153-155	mechanistic target of rapamycin kinase	Rattus norvegicus	58-62	
24989011-7	2014	The results indicate that SA can rescue CoCl2-induced repression of REDD1/mTOR/ p70S6K signal transduction in PC12 cells.	rhodioloside	26-28	mechanistic target of rapamycin kinase	Rattus norvegicus	74-78	
24989011-8	2014	Our data demonstrate that SA is able to attenuate CoCl2-induced hypoxia damage and mTOR signaling repression, suggesting that SA may protect brain neurons from ischemic injury through mTOR signaling, and provide new insights into the prevention and treatment of cerebral ischemic.	rhodioloside	26-28	mechanistic target of rapamycin kinase	Rattus norvegicus	83-87	
24989011-8	2014	Our data demonstrate that SA is able to attenuate CoCl2-induced hypoxia damage and mTOR signaling repression, suggesting that SA may protect brain neurons from ischemic injury through mTOR signaling, and provide new insights into the prevention and treatment of cerebral ischemic.	rhodioloside	26-28	mechanistic target of rapamycin kinase	Rattus norvegicus	184-188	
24989011-8	2014	Our data demonstrate that SA is able to attenuate CoCl2-induced hypoxia damage and mTOR signaling repression, suggesting that SA may protect brain neurons from ischemic injury through mTOR signaling, and provide new insights into the prevention and treatment of cerebral ischemic.	rhodioloside	126-128	mechanistic target of rapamycin kinase	Rattus norvegicus	83-87	
24989011-8	2014	Our data demonstrate that SA is able to attenuate CoCl2-induced hypoxia damage and mTOR signaling repression, suggesting that SA may protect brain neurons from ischemic injury through mTOR signaling, and provide new insights into the prevention and treatment of cerebral ischemic.	rhodioloside	126-128	mechanistic target of rapamycin kinase	Rattus norvegicus	184-188	
29148269-7	2018	The results showed that Sal prevents apoptosis of PC12 cells in coculture with LPS-induced M1 BV-2 microglia, also the inflammatory secretion phenotype of M1 BV-2 microglia was suppressed by Sal, and further studies demonstrated that autophagic flux regulation through AMPK/mTOR pathway was involved in Sal regulated microglia polarization after SCI.	rhodioloside	24-27	mechanistic target of rapamycin kinase	Rattus norvegicus	274-278	
29148269-8	2018	Overall, our study illustrated that Sal could promote spinal cord injury functional recovery in rats, and the mechanism may relate to its microglia polarization modulation through AMPK-/mTOR-mediated autophagic flux stimulation.	rhodioloside	36-39	mechanistic target of rapamycin kinase	Rattus norvegicus	186-190	
29864934-13	2018	To conclude, this study provide in vitro evidence that salidroside protected NSCs against hypoxia-induced injury by up-regulation of miR-210, which in turn inhibited the expression of BTG3 and activated PI3K/AKT/mTOR signaling pathway.	rhodioloside	55-66	mechanistic target of rapamycin kinase	Rattus norvegicus	212-216	
28905500-0	2017	Salidroside suppressing LPS-induced myocardial injury by inhibiting ROS-mediated PI3K/Akt/mTOR pathway in vitro and in vivo.	rhodioloside	0-11	mechanistic target of rapamycin kinase	Rattus norvegicus	90-94	
27357827-10	2016	Salidroside inhibited the glutamate-induced dissociation of the Bcl-2-Beclin-1 complex with minor affects on the PI3K/Akt/mTOR signaling pathways.	rhodioloside	0-11	mechanistic target of rapamycin kinase	Rattus norvegicus	122-126