PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27174133-16 2016 Arsenite-induced alteration in heart Nrf-2, HO-1, Smad-3, and TGF-beta mRNA expression were significantly restored (p < 0.05) by naringin (40 and 80 mg/kg) treatment. naringin 132-140 transforming growth factor, beta 1 Rattus norvegicus 62-70 27174133-19 2016 CONCLUSION: The results of present investigation suggest that naringin ameliorates arsenite-induced cardiotoxicity via modulation of TGF-beta/Smad-3 and Nrf-2/HO-1 pathways along with a reduction in myocardial apoptosis. naringin 62-70 transforming growth factor, beta 1 Rattus norvegicus 133-141 26337322-11 2015 In conclusion, naringin treatment ameliorates arsenic-induced renal and hepatic damage in rats due its antioxidant and anti-inflammatory properties via down-regulation of elevated oxido-nitrosative stress, KIM-1, Caspase-3, TGF-beta, and TNF-alpha levels. naringin 15-23 transforming growth factor, beta 1 Rattus norvegicus 224-232 24880026-9 2014 Naringin treatment at 40 and 80 mg/kg resulted in significant (P<0.05) up-regulation of mRNA expression of growth factor (IFG-1, TGF-beta and VEGF-c), Ang-1 and collagen-1 whereas mRNA expression of inflammatory mediators (TNF-alpha, IL-1beta and IL-6) was down-regulated. naringin 0-8 transforming growth factor, beta 1 Rattus norvegicus 132-140