PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24118820-7 2014 These injuries were significantly attenuated by the pre-treatment of cells with either naringin or SB203580 (a selective inhibitor of p38 MAPK) or U0126 (a selective inhibitor of extracellular signal regulated kinase 1/2, ERK1/2) or SP600125 (a selective inhibitor of c-jun N-termanal kinase, JNK) before exposure to HG, respectively. naringin 87-95 mitogen activated protein kinase 14 Rattus norvegicus 134-137 24118820-10 2014 In conclusion, our findings provide new evidence for the first time that naringin protects against HG-induced injuries by inhibiting the activation of MAPK (p38 MAPK, ERK1/2 and JNK) and oxidative stress in H9c2 cells. naringin 73-81 mitogen activated protein kinase 14 Rattus norvegicus 157-160 24399619-0 2014 Inhibition of the leptin-induced activation of the p38 MAPK pathway contributes to the protective effects of naringin against high glucose-induced injury in H9c2 cardiac cells. naringin 109-117 mitogen activated protein kinase 14 Rattus norvegicus 51-54 24399619-2 2014 In this study, we demonstrate that naringin, a citrus flavonone, protects cardiomyoblasts (H9c2 cells) against high glucose (HG)-induced apoptosis by modulating the activation of the p38 MAPK pathway. naringin 35-43 mitogen activated protein kinase 14 Rattus norvegicus 183-186 24399619-3 2014 We investigated the hypothesis that naringin prevents HG-induced injury by inhibiting the leptin-induced activation of the p38 MAPK pathway in H9c2 cells. naringin 36-44 mitogen activated protein kinase 14 Rattus norvegicus 123-126 26967518-2 2016 The effects of naringin on hyperglycemia-induced myocardial fibrotic changes and its putative effects on PKC-beta and p38 protein expression in type 1 rat model of diabetes are hereby investigated. naringin 15-23 mitogen activated protein kinase 14 Rattus norvegicus 118-121 26967518-9 2016 CONCLUSIONS: Naringin"s amelioration of myocardial fibrosis by modulating p38 and PKC-beta protein expression possibly through its known antioxidant actions and may therefore be useful in retarding the progression of fibrosis in a diabetic heart. naringin 13-21 mitogen activated protein kinase 14 Rattus norvegicus 74-77