PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29456667-8	2018	Treatment with naringin was able to significantly ameliorate the NF-kappaB-induced overexpression of P-gp (P<0.05).	naringin	15-23	nuclear factor kappa B subunit 1	Homo sapiens	65-74	
31927560-0	2019	Naringin Protects Against Interleukin 1beta (IL-1beta)-Induced Human Nucleus Pulposus Cells Degeneration via Downregulation Nuclear Factor kappa B (NF-kappaB) Pathway and p53 Expression.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	124-146	
31927560-0	2019	Naringin Protects Against Interleukin 1beta (IL-1beta)-Induced Human Nucleus Pulposus Cells Degeneration via Downregulation Nuclear Factor kappa B (NF-kappaB) Pathway and p53 Expression.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	148-157	
26861272-2	2016	The aim of this study is to investigate the impact of naringin on the TNF-alpha-induced expressions of cell adhesion molecules, chemokines and NF-kappaB signaling pathway in human umbilical vein endothelial cells (HUVECs).	naringin	54-62	nuclear factor kappa B subunit 1	Homo sapiens	143-152	
26861272-0	2016	The Anti-Atherosclerotic Effect of Naringin Is Associated with Reduced Expressions of Cell Adhesion Molecules and Chemokines through NF-kappaB Pathway.	naringin	35-43	nuclear factor kappa B subunit 1	Homo sapiens	133-142	
26861272-6	2016	Naringin significantly inhibited TNF-alpha-induced nuclear translocation of NF-kappaB, which resulted from the inhibited phosphorylation of IKKalpha/beta, IkappaB-alpha and NF-kappaB.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	76-85	
26861272-6	2016	Naringin significantly inhibited TNF-alpha-induced nuclear translocation of NF-kappaB, which resulted from the inhibited phosphorylation of IKKalpha/beta, IkappaB-alpha and NF-kappaB.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	173-182	
26861272-7	2016	Altogether, we proposed that naringin modulated TNF-alpha-induced expressions of cell adhesion molecules and chemokines through the inhibition of TNF-alpha-induced activation of IKK/NF-kappaB signaling pathway to exert the anti-atherosclerotic effect.	naringin	29-37	nuclear factor kappa B subunit 1	Homo sapiens	182-191	
25391245-0	2014	Naringin inhibits TNF-alpha induced oxidative stress and inflammatory response in HUVECs via Nox4/NF-kappa B and PI3K/Akt pathways.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	98-108	
25174821-0	2014	Naringin inhibits growth and induces apoptosis by a mechanism dependent on reduced activation of NF-kappaB/COX-2-caspase-1 pathway in HeLa cervical cancer cells.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	97-106	
22766066-1	2012	Naringenin, the aglycone of naringin, has been reported to attenuate MUC5AC secretion by inhibiting activity of nuclear factor kappa B (NF-kappaB) via EGFR-PI3K-Akt/ERK MAPKinase signaling pathways.	naringin	28-36	nuclear factor kappa B subunit 1	Homo sapiens	112-134	
33086930-2	2020	Our previous studies showed that the traditional Chinese medicine naringin significantly inhibited the proliferation of platinum-resistant ovarian cancer cells in vitro, and that the mechanism may be related to the NF-kappaB pathway.	naringin	66-74	nuclear factor kappa B subunit 1	Homo sapiens	215-224	
22766066-1	2012	Naringenin, the aglycone of naringin, has been reported to attenuate MUC5AC secretion by inhibiting activity of nuclear factor kappa B (NF-kappaB) via EGFR-PI3K-Akt/ERK MAPKinase signaling pathways.	naringin	28-36	nuclear factor kappa B subunit 1	Homo sapiens	136-145	
22766066-4	2012	The results showed that naringin of 100 muM not only significantly decreased EGF-induced overexpressions of both MUC5AC mucin and mRNA in A549 cells, but also suppressed the phosphorylation of EGF receptor, p38 mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK1/2), and c-Jun N-terminal kinase (JNK), as well as nucleus NF-kappaB p65 and AP-1.	naringin	24-32	nuclear factor kappa B subunit 1	Homo sapiens	354-363	
20159712-8	2010	Naringin also suppressed high glucose-induced increment of NF-kappaB expression in the cell nuclei of HUVECs.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	59-68	
20159712-9	2010	CONCLUSION: Naringin can suppress high glucose-induced vascular inflammation possibly by inhibiting ROS production and NF-kappaB activation in HUVECs.	naringin	12-20	nuclear factor kappa B subunit 1	Homo sapiens	119-128	
32979141-0	2021	Naringin Combined with NF-kappaB Inhibition and Endoplasmic Reticulum Stress Induces Apoptotic Cell Death via Oxidative Stress and the PERK/eIF2alpha/ATF4/CHOP Axis in HT29 Colon Cancer Cells.	naringin	0-8	nuclear factor kappa B subunit 1	Homo sapiens	23-32