PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33755912-0 2021 Indole-3-carboxaldehyde regulates RSV-induced inflammatory response in RAW264.7 cells by moderate inhibition of the TLR7 signaling pathway. indole-3-carbaldehyde 0-23 toll-like receptor 7 Mus musculus 116-120 33755912-8 2021 Furthermore, we revealed that indole-3-carboxaldehyde suppressed transcription of IFN-alpha by inhibiting RSV-induced TLR7 expression in RAW264.7 cells. indole-3-carbaldehyde 30-53 toll-like receptor 7 Mus musculus 118-122 33755912-9 2021 Additionally, indole-3-carboxaldehyde inhibited RSV-induced NF-kappaB signalling activation in a TLR7-MyD88-dependent manner. indole-3-carbaldehyde 14-37 toll-like receptor 7 Mus musculus 97-101 33755912-10 2021 Together, our findings suggest that indole-3-carboxaldehyde inhibited RSV-induced inflammatory injury by moderate regulation of TLR7 signaling pathway and did not significantly affect the viral clearance competence of the innate immune system. indole-3-carbaldehyde 36-59 toll-like receptor 7 Mus musculus 128-132