PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26759700-0	2016	PXR Mediated Protection against Liver Inflammation by Ginkgolide A in Tetrachloromethane Treated Mice.	ginkgolide A	54-66	nuclear receptor subfamily 1, group I, member 2	Mus musculus	0-3	
32682918-0	2020	Ginkgolide-A attenuates bacterial translocation through activating PXR and improving antimicrobial peptide Reg 3A in experimental cirrhosis.	ginkgolide A	0-12	nuclear receptor subfamily 1, group I, member 2	Mus musculus	67-70	
32682918-3	2020	We previously showed that Ginkgolide-A (GA), a natural PXR ligand, attenuated BT in cirrhotic mice by abrogating inflammation along the gut-liver-axis, and by protecting small intestinal tight junctions (TJ).	ginkgolide A	26-38	nuclear receptor subfamily 1, group I, member 2	Mus musculus	55-58	
32682918-3	2020	We previously showed that Ginkgolide-A (GA), a natural PXR ligand, attenuated BT in cirrhotic mice by abrogating inflammation along the gut-liver-axis, and by protecting small intestinal tight junctions (TJ).	ginkgolide A	40-42	nuclear receptor subfamily 1, group I, member 2	Mus musculus	55-58	
32682918-4	2020	Here, we aimed to investigate the effect of GA in activating PXR and associated antimicrobial peptides (AMPs) in regulating BT in experimental cirrhosis.	ginkgolide A	44-46	nuclear receptor subfamily 1, group I, member 2	Mus musculus	61-64	
32682918-12	2020	CONCLUSION: The study showed for the first time that, GA treatment to cirrhotic rodents attenuates BT, by improving PXR and Reg3A expression.	ginkgolide A	54-56	nuclear receptor subfamily 1, group I, member 2	Mus musculus	116-119	
31697926-0	2020	Pregnane X receptor activation by its natural ligand Ginkgolide-A improves tight junction proteins expression and attenuates bacterial translocation in cirrhosis.	ginkgolide A	53-63	nuclear receptor subfamily 1, group I, member 2	Mus musculus	0-19	
31697926-5	2020	This study aims to investigate the effect of GA in activating PXR and improving associated tight junction integrity and reducing bacterial translocation in gut-liver axis of CCl4 induced cirrhosis model.	ginkgolide A	45-47	nuclear receptor subfamily 1, group I, member 2	Mus musculus	62-65	
31697926-10	2020	Treatment with GA to cirrhotic mice significantly (p < 0.05) induced the expression of both hepatic and small intestinal PXR, CYP3A, ZO-1 and Occludin.	ginkgolide A	15-17	nuclear receptor subfamily 1, group I, member 2	Mus musculus	124-127	
31697926-14	2020	CONCLUSION: In conclusion, our data supports the hypothesis that, GA treatment to CCl4 induced cirrhotic mice, activated hepatic and small intestinal PXR and diminished inflammation, thereby improving tight junction integrity and attenuating bacterial translocation.	ginkgolide A	66-68	nuclear receptor subfamily 1, group I, member 2	Mus musculus	150-153	
26759700-3	2016	Ginkgolide A, one main component of Ginkgo biloba extracts (GBE), activated PXR and enhanced PXR expression level, displayed both significant therapeutic effect and preventive effect against CCl4-induced mouse hepatitis.	ginkgolide A	0-12	nuclear receptor subfamily 1, group I, member 2	Mus musculus	76-79	
26759700-3	2016	Ginkgolide A, one main component of Ginkgo biloba extracts (GBE), activated PXR and enhanced PXR expression level, displayed both significant therapeutic effect and preventive effect against CCl4-induced mouse hepatitis.	ginkgolide A	0-12	nuclear receptor subfamily 1, group I, member 2	Mus musculus	93-96	
26759700-4	2016	siRNA-mediated decrease of PXR expression significantly reduced the efficacy of Ginkgolide A in treating CCl4-induced inflammation in mice.	ginkgolide A	80-92	nuclear receptor subfamily 1, group I, member 2	Mus musculus	27-30