PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11226385-5 2001 Ginkgolide A, ginkgolide B, or bilobalide (0.25 to 1.0 microg/mL) caused a 30-65% reduction in the levels of NO metabolites released by THP-1 macrophages after 4 hr of incubation, with a corresponding decrease in iNOS activity. ginkgolide A 0-12 nitric oxide synthase 2 Homo sapiens 213-217 12619887-10 2003 EGb and its terpenoids (ginkgolide A, ginkgolide B and bilobalide) could antagonize the homocysteine effect on iNOS expression in macrophages via their antioxidant effect resulting in attenuation of NF-kappaB activation. ginkgolide A 24-36 nitric oxide synthase 2 Homo sapiens 111-115 11226385-8 2001 Taken together, these results suggest that ginkgolide A, ginkgolide B, and bilobalide may contribute to the selective inhibitory effect of EGb on iNOS expression without affecting eNOS-mediated NO production. ginkgolide A 43-55 nitric oxide synthase 2 Homo sapiens 146-150 11226385-6 2001 Western immunoblotting analysis coupled with a nuclease protection assay and reverse transcription-polymerase chain reaction revealed a concomitant reduction in the levels of iNOS protein mass and mRNA in ginkgolide A-, ginkgolide B-, or bilobalide-treated macrophages. ginkgolide A 205-217 nitric oxide synthase 2 Homo sapiens 175-179