PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28672809-6 2017 Further investigation showed the down-regulation of B-cell lymphoma 2 (Bcl-2), up-regulation of Bcl-2 homologous antagonist/killer (Bak), and nuclear translocation of apoptosis-inducing factor (AIF) in montelukast-treated lung cancer cells. montelukast 202-213 B cell leukemia/lymphoma 2 Mus musculus 52-69 24456746-5 2014 Blockade of CysLT1R by repeated treatment with montelukast (1 or 2 mg/kg, ig, 4 weeks) reduced Abeta1-42-induced CysLT1R expression and also suppressed Abeta1-42-induced increments of NF-kappaB p65, TNF-alpha, IL-1beta and caspase-3 activation, and Bcl-2 downregulation in the hippocampus and cortex. montelukast 47-58 B cell leukemia/lymphoma 2 Mus musculus 249-254