PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33872698-0	2021	Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice.	paricalcitol	0-12	sirtuin 1	Mus musculus	115-120	
33872698-12	2021	Interesting, we found that paricalcitol prevented the downregulation of oxidative stress-induced Sirt1 expression in the BDL mice and t-BHP-induced BECs models.	paricalcitol	27-39	sirtuin 1	Mus musculus	97-102	
33872698-13	2021	Moreover, paricalcitol suppressed cell senescence through a Sirt1-dependent pathway.	paricalcitol	10-22	sirtuin 1	Mus musculus	60-65	
33872698-15	2021	CONCLUSION: Paricalcitol alleviated cholestatic liver injury through promoting the repair of damaged bile ducts and reducing oxidative stress-induced cell senescence of the bile duct via modulating Sirt1 pathway.	paricalcitol	12-24	sirtuin 1	Mus musculus	198-203