PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33850552-6	2021	The expression of osteogenic genes, including ALP, collagen I, runt-related transcription factor 2, osterix, osteopontin, osteocalcin, osteoprotegerin and estrogen receptor alpha, increased significantly after irisin treatment.	irisin	210-216	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	Mus musculus	135-150	
35290462-6	2022	Cells were treated with irisin (100 ng/ml) for various time lengths ranging from 0 to 72 hours, and then qRT-PCR was used to detect the expression of osteoclastogenesis-related genes, including RANKL, IL-6, M-CSF, OPG, Wnt5A, Sema3A.	irisin	24-30	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	Mus musculus	214-217	
32768686-13	2020	Irisin significantly increased the proliferation of osteocytes, protected them from apoptosis, and maintained cellular activity by regulating the expression of Bax, Bcl-2, and osteoprotegerin/receptor activator of nuclear factor (NF)-kB-ligand (OPG/Rankl).	irisin	0-6	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	Mus musculus	245-248