PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34479089-9 2021 Irisin treatment significantly alleviated ROS accumulation, autophagy disorder, NF-kappaB-Snail pathway activation as well as the phenotype of EndMT by targeting uncoupling protein 2 (UCP2). irisin 0-6 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 162-182 32934963-0 2020 Irisin Pretreatment Protects Kidneys against Acute Kidney Injury Induced by Ischemia/Reperfusion via Upregulating the Expression of Uncoupling Protein 2. irisin 0-6 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 132-152 32934963-8 2020 Irisin pretreatment ameliorated the cell apoptosis induced by H/R, while transfection of UCP2 siRNA significantly reduced the protective effect of irisin in cells after H/R. irisin 147-153 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 89-93 32934963-9 2020 In addition, AMPK signaling may be involved in irisin-mediated upregulation of UCP2 in a renal proximal tubular epithelial cell (PTEC) model. irisin 47-53 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 79-83 34479089-9 2021 Irisin treatment significantly alleviated ROS accumulation, autophagy disorder, NF-kappaB-Snail pathway activation as well as the phenotype of EndMT by targeting uncoupling protein 2 (UCP2). irisin 0-6 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 184-188 34479089-12 2021 Irisin treatment could partially reverse this phenomenon by regulating UCP2. irisin 0-6 uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus 71-75