PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28166200-7 2017 Following knockdown of MARCKS in RCC cells, the IC50 of the multikinase inhibitor regorafenib was reduced. regorafenib 82-93 myristoylated alanine rich protein kinase C substrate Homo sapiens 23-29 28166200-8 2017 Surprisingly, attenuation of MARCKS using the MPS (MARCKS phosphorylation site domain) peptide synergistically interacted with regorafenib treatment and decreased survival of kidney cancer cells through inactivation of AKT and mTOR. regorafenib 127-138 myristoylated alanine rich protein kinase C substrate Homo sapiens 29-35 28166200-8 2017 Surprisingly, attenuation of MARCKS using the MPS (MARCKS phosphorylation site domain) peptide synergistically interacted with regorafenib treatment and decreased survival of kidney cancer cells through inactivation of AKT and mTOR. regorafenib 127-138 myristoylated alanine rich protein kinase C substrate Homo sapiens 51-57