PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12093614-2 2002 The hypothesis that perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), and certain related perfluorooctanesulfonamide-based fluorochemicals (PFOSAs) can interfere with the binding affinity of L-FABP for fatty acids was tested. perfluorooctane sulfonic acid 20-44 fatty acid binding protein 1 Rattus norvegicus 201-207 12093614-5 2002 PFOS exhibited the highest level of inhibition of DAUDA-L-FABP binding in the competitive binding assays, followed by N-EtFOSA, WY, and, with equal IC(50)s, N-EtFOSE and PFOA. perfluorooctane sulfonic acid 0-4 fatty acid binding protein 1 Rattus norvegicus 56-62 30735364-7 2019 The binding characteristics of the PFOS alternatives for LFABP were elaborated to explore how the different structural modifications of molecules influenced the underlying binding mechanisms. perfluorooctane sulfonic acid 35-39 fatty acid binding protein 1 Rattus norvegicus 57-62 30735364-9 2019 Our findings from the combination of experimental exposure and computational model can provide helpful information to design potential alternatives of PFOS with weak LFABP binding capability and low liver accumulation. perfluorooctane sulfonic acid 151-155 fatty acid binding protein 1 Rattus norvegicus 166-171