PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34861291-8	2022	These results indicate that mouse PPARalpha can be activated in the liver by PFOS causing increased expression of Acox1, Cyp4a10 and histopathological changes in the liver.	perfluorooctane sulfonic acid	77-81	acyl-Coenzyme A oxidase 1, palmitoyl	Mus musculus	114-119	
34861291-9	2022	While histopathological analyses indicated the presence of mouse PPARalpha-dependent hepatic peroxisome proliferation in wild-type (a response associated with activation of PPARalpha) and a similar phenotype in PPARA-humanized mice, the lack of increased Acox1 and Cyp4a10 mRNA by PFOS in PPARA-humanized mice indicates that the human PPARalpha was not as responsive to PFOS as mouse PPARalpha with this dose regimen.	perfluorooctane sulfonic acid	281-285	acyl-Coenzyme A oxidase 1, palmitoyl	Mus musculus	255-260