PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
28985536-8	2018	At >= 500 nM, PFOS downregulated Lhcgr, inhibited BCL-2 and increased BAX levels to cause Leydig cell apoptosis.	perfluorooctane sulfonic acid	17-21	BCL2, apoptosis regulator	Rattus norvegicus	53-58	
31588057-0	2019	Perfluorooctane sulfonate induces apoptosis via activation of FoxO3a and upregulation of proapoptotic Bcl-2 proteins in PC12 cells.	perfluorooctane sulfonic acid	0-25	BCL2, apoptosis regulator	Rattus norvegicus	102-107	
24616003-8	2015	The mRNA and protein expression levels of p53, bax, cytochrome c, caspase-9, and caspase-3 in the offspring"s heart were enhanced in various PFOS-treated groups, meanwhile, the bcl-2 expression levels were decreased.	perfluorooctane sulfonic acid	141-145	BCL2, apoptosis regulator	Rattus norvegicus	177-182	
21440054-5	2012	The results showed that maternal exposure to 2.0mg/kgd PFOS caused severe histopathological changes along with marked oxidative injuries and cell apoptosis in offspring lungs; at the same time, the ratio of Bax to Bcl-2, release of cytochrome c (Cyt c) from mitochondria to cytoplasm, expressions of Fas and Fas-L, and activities of caspase-3, -8 and -9 were up-regulated correspondingly.	perfluorooctane sulfonic acid	55-59	BCL2, apoptosis regulator	Rattus norvegicus	214-219