PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31454128-9	2019	Consequently, it could be presumed that Sita as well as Cur administration can limit the poisonous impacts of DLM by their free radical-scavenging, strong antioxidant, and Nrf2/HO-1 pathway upregulation activity.	Sitagliptin Phosphate	40-44	NFE2 like bZIP transcription factor 2	Rattus norvegicus	172-176	
33453244-0	2021	Activation of autophagy by sitagliptin attenuates cadmium-induced testicular impairment in rats: Targeting AMPK/mTOR and Nrf2/HO-1 pathways.	Sitagliptin Phosphate	27-38	NFE2 like bZIP transcription factor 2	Rattus norvegicus	121-125	
33453244-12	2021	In tandem, sitagliptin suppressed oxidative stress through lowering of lipid peroxides and activating Nrf2/HO-1 pathway by upregulating the protein expression of Nrf2, and the downstream effectors HO-1 and GPx.	Sitagliptin Phosphate	11-22	NFE2 like bZIP transcription factor 2	Rattus norvegicus	102-106	
33453244-12	2021	In tandem, sitagliptin suppressed oxidative stress through lowering of lipid peroxides and activating Nrf2/HO-1 pathway by upregulating the protein expression of Nrf2, and the downstream effectors HO-1 and GPx.	Sitagliptin Phosphate	11-22	NFE2 like bZIP transcription factor 2	Rattus norvegicus	162-166	
33453244-13	2021	SIGNIFICANCE: Sitagliptin attenuated Cd-induced testicular injury via boosting the autophagy/apoptosis ratio through activation of AMPK/mTOR and Nrf2/HO-1 pathways.	Sitagliptin Phosphate	14-25	NFE2 like bZIP transcription factor 2	Rattus norvegicus	145-149	
31301179-0	2019	Activation of Nrf2 signaling by sitagliptin and quercetin combination against beta-amyloid induced Alzheimer"s disease in rats.	Sitagliptin Phosphate	32-43	NFE2 like bZIP transcription factor 2	Rattus norvegicus	14-18	
30714645-0	2019	Protective role of sitagliptin against oxidative stress in a kainic acid-induced status epilepticus in rats models via Nrf2/HO-1 pathway.	Sitagliptin Phosphate	19-30	NFE2 like bZIP transcription factor 2	Rattus norvegicus	119-123	
30714645-10	2019	Sita Pretreatment showed significant elevation in expression of Nrf2 and HO-1 proteins in hippocampus region of the brain.	Sitagliptin Phosphate	0-4	NFE2 like bZIP transcription factor 2	Rattus norvegicus	64-68	
30128961-11	2019	Phosphorylation of PI3K and Nrf2 nuclear translocation under high-glucose concentration condition was induced by sitagliptin in HRMC.	Sitagliptin Phosphate	113-124	NFE2 like bZIP transcription factor 2	Rattus norvegicus	28-32	
30128961-13	2019	CONCLUSIONS: Sitagliptin may induce HO-1 expression via activation of PI3K and Nrf2 in rats with diabetic nephropathy; HO-1 can improve the oxidative stress of diabetic nephropathy, eventually protect from diabetic nephropathy.	Sitagliptin Phosphate	13-24	NFE2 like bZIP transcription factor 2	Rattus norvegicus	79-83	
28652790-0	2017	Sitagliptin ameliorates oxidative stress in experimental diabetic nephropathy by diminishing the miR-200a/Keap-1/Nrf2 antioxidant pathway.	Sitagliptin Phosphate	0-11	NFE2 like bZIP transcription factor 2	Rattus norvegicus	113-117	
29101811-6	2018	Sitagliptin and/or resveratrol induced significant improvement of the renal functions with significant increase in tissue antioxidant defenses and Nrf2/HO-1 content associated with significant decrease in tissue LDH, TGF-beta1, TNF-alpha, IL-6 and STAT3 and alleviated the histopathological and immunohistochemical changes compared to the untreated clear cell renal cell carcinoma group.	Sitagliptin Phosphate	0-11	NFE2 like bZIP transcription factor 2	Rattus norvegicus	147-151