PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21756066-4	2011	For the first time, The results of this study showed for the first time that nilotinib induces apoptosis through upregulating ceramide synthase genes and downregulating SK-1 in CML cells in addition to inhibition of BCR/ABL.	nilotinib	77-86	sphingosine kinase 1	Homo sapiens	169-173	
23098068-6	2013	There was an up-regulation of antiapoptotic BCR/ABL, GCS and SK-1 genes and MRP1 transporter gene and down-regulation of apoptotic Bax and CerS1 genes in nilotinib-resistant cells.	nilotinib	154-163	sphingosine kinase 1	Homo sapiens	61-65	
23098068-8	2013	Inhibiton of GCS and SK-1 restored nilotinib sensitivity.	nilotinib	35-44	sphingosine kinase 1	Homo sapiens	21-25