PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29989011-7	2018	However, at 10 microM TQ, CYP2C9 enzyme activity was maximally inhibited by 69.69%, followed by CYP3A4 (23.59%) > CYP1A2 (23.51%) > CYP2D6 (11.42%).	thymoquinone	22-24	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	26-32	
29989011-1	2018	The aim of the present study was to investigate the potential effect of thymoquinone (TQ) on the metabolic activity of four major drug metabolizing enzymes in human liver microsomes, namely cytochrome P450 (CYP) 1A2, CYP2C9, CYP2D6 and CYP3A4.	thymoquinone	72-84	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	217-223	
29989011-1	2018	The aim of the present study was to investigate the potential effect of thymoquinone (TQ) on the metabolic activity of four major drug metabolizing enzymes in human liver microsomes, namely cytochrome P450 (CYP) 1A2, CYP2C9, CYP2D6 and CYP3A4.	thymoquinone	86-88	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	217-223	
29989011-2	2018	The inhibition of CYP enzymatic activities by TQ was evaluated by incubating typical substrates (phenacetin for CYP1A2, tolbutamide for CYP2C9, dextromethorphan for CYP2D6, and testosterone for CYP3A4) with human liver microsomes and NADPH in the absence or presence of TQ (1, 10 and 100 microM).	thymoquinone	46-48	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	136-142