PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26500095-9 2016 Interestingly, when cells were treated with high dose TQ, several growth factors such as Vegf and Egf were upregulated and several pro-apoptotic factors such as caspases were downregulated possibly pointing out key pathways manipulated by cancer cells to resist against TQ. thymoquinone 54-56 caspase 12 Mus musculus 161-169 26500095-11 2016 TQ has also been shown to induce protein levels of cleaved Caspase-3, Caspase-7, and Caspase-12 and PARP and to reduce phosphorylated p65 and Akt1. thymoquinone 0-2 caspase 12 Mus musculus 85-95