PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33844597-8	2021	RESULTS: A group of known AChE inhibitors, such as donepezil, ambenonium dichloride, and tacrine hydrochloride, as well as many previously unreported AChE inhibitors, such as chelerythrine chloride and cilostazol, were identified in this study.	chelerythrine	175-197	acetylcholinesterase (Cartwright blood group)	Homo sapiens	150-154	
23062825-6	2012	Analysis of the kinetic mechanism of the AChE inhibition revealed chelerythrine as a mixed inhibitor.	chelerythrine	66-79	acetylcholinesterase (Cartwright blood group)	Homo sapiens	41-45	
23062825-7	2012	Using molecular docking studies, it was further proven that chelerythrine binds on both the catalytic site and the peripheral anionic site (PAS) of the AChE.	chelerythrine	60-73	acetylcholinesterase (Cartwright blood group)	Homo sapiens	152-156	
23062825-10	2012	This approach enabled for the first time to identify a cholinesterase inhibitor of natural origin-chelerythrine-acting on AChE and BChE with a dual ability to inhibit Abeta aggregation as well as to disaggregate preformed Abeta aggregates.	chelerythrine	98-111	acetylcholinesterase (Cartwright blood group)	Homo sapiens	122-126	
32454229-0	2020	Simple analogues of natural product chelerythrine: Discovery of a novel anticholinesterase 2-phenylisoquinolin-2-ium scaffold with excellent potency against acetylcholinesterase.	chelerythrine	36-49	acetylcholinesterase (Cartwright blood group)	Homo sapiens	157-177	
32454229-2	2020	The activity evaluation led to the discovery of seven compounds with potent anti-acetylcholinesterase activity with IC50 values of <=0.72 muM, superior to chelerythrine and standard drugs galantamine.	chelerythrine	155-168	acetylcholinesterase (Cartwright blood group)	Homo sapiens	81-101	
28294544-8	2017	A group of inhibitors were identified from this study, including known (e.g. physostigmine and neostigmine bromide) and potential novel AChE inhibitors (e.g. chelerythrine chloride and cilostazol).	chelerythrine	158-180	acetylcholinesterase (Cartwright blood group)	Homo sapiens	136-140	
30108764-1	2017	By analogy with the natural product chelerythrine, which has been identified as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), we prepared a small series of 8-hydroxy-2,7-naphthyridin-2-ium salts.	chelerythrine	36-49	acetylcholinesterase (Cartwright blood group)	Homo sapiens	101-121	
30108764-1	2017	By analogy with the natural product chelerythrine, which has been identified as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), we prepared a small series of 8-hydroxy-2,7-naphthyridin-2-ium salts.	chelerythrine	36-49	acetylcholinesterase (Cartwright blood group)	Homo sapiens	123-127