PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22238372-6	2012	Pretreatment of trophoblasts with selective inhibitors of I-kB kinase activity (parthenolide and TPCA-1) reduced oxysterol- and LPS-stimulated inflammatory responses, consistent with the involvement of the nuclear factor kappa B (NF-kappaB) pathway downstream of TLR4 signalling.	parthenolide	80-92	toll like receptor 4	Homo sapiens	263-267	
25971793-0	2015	Sesquiterpene lactone parthenolide attenuates production of inflammatory mediators by suppressing the Toll-like receptor-4-mediated activation of the Akt, mTOR, and NF-kappaB pathways.	parthenolide	22-34	toll like receptor 4	Homo sapiens	102-122	
25971793-4	2015	Using human keratinocytes, we investigated the effect of parthenolide on the inflammatory mediator production in relation to the Toll-like receptor-4-mediated-Akt/mTOR and NF-kappaB pathways, which regulate the transcription genes involved in immune and inflammatory responses.	parthenolide	57-69	toll like receptor 4	Homo sapiens	129-149	
25971793-6	2015	The results show that parthenolide appears to attenuate the lipopolysaccharide-stimulated production of inflammatory mediators in keratinocytes by suppressing the Toll-like receptor-4-mediated activation of the Akt, mTOR, and NF-kappaB pathways.	parthenolide	22-34	toll like receptor 4	Homo sapiens	163-183	
25841439-0	2015	Parthenolide inhibits LPS-induced inflammatory cytokines through the toll-like receptor 4 signal pathway in THP-1 cells.	parthenolide	0-12	toll like receptor 4	Homo sapiens	69-89