PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17556802-6	2007	Parthenolide inhibited proliferation of all three types of cancer cells (A549, TE671, HT-29) and HUVEC with the following IC(50) values (in muM): 4.3, 6.5, 7.0 and 2.8, respectively.	parthenolide	0-12	latexin	Homo sapiens	140-143	
31030314-3	2020	They exhibited better cytostatic effects than etoposide (GI50 = 0.56-36.62 muM), parthenolide (GI50 = 3.58-25.97 muM) and VK3 (GI50 = 3.41-22.59 muM) against several of the cancer cell lines.	parthenolide	81-93	latexin	Homo sapiens	113-116	
31030314-3	2020	They exhibited better cytostatic effects than etoposide (GI50 = 0.56-36.62 muM), parthenolide (GI50 = 3.58-25.97 muM) and VK3 (GI50 = 3.41-22.59 muM) against several of the cancer cell lines.	parthenolide	81-93	latexin	Homo sapiens	113-116	
29216473-4	2018	Likewise, phosphorylation of extracellular signal-regulated kinase (ERK) 1/2 in activated Jurkat cells was inhibited by these five compounds, with the most potent being parthenolide and estafiatin (IC50 = 13.8 and 15.4 muM, respectively).	parthenolide	169-181	latexin	Homo sapiens	219-222	
30484368-6	2019	The half-maximal inhibitory concentration (IC50) of PTL on the activity of UGT1A1 was determined to be 64.4 muM.	parthenolide	52-55	latexin	Homo sapiens	108-111	
30484368-7	2019	Inhibition kinetics determination showed that PTL exerted noncompetitive inhibition toward UGT1A1, and the inhibition kinetic constant (Ki) was determined to be 12.1 muM.	parthenolide	46-49	latexin	Homo sapiens	166-169	
30739826-5	2019	Compound 7d exhibited the most potent activity against different breast cancer cells with IC50 values ranging from 0.20 muM to 0.27 muM, which demonstrated 11.6- to 18.6-fold improvement comparing to that of the parent compound parthenolide with IC50 values of 2.68-4.63 muM.	parthenolide	228-240	latexin	Homo sapiens	132-135	
30739826-5	2019	Compound 7d exhibited the most potent activity against different breast cancer cells with IC50 values ranging from 0.20 muM to 0.27 muM, which demonstrated 11.6- to 18.6-fold improvement comparing to that of the parent compound parthenolide with IC50 values of 2.68-4.63 muM.	parthenolide	228-240	latexin	Homo sapiens	132-135	
22369858-8	2012	In the taxol resistant cell lines, the IC50 values of paclitaxel and parthenolide were 233nM and 32muM, respectively, while the combination had an IC(50) of 128nM.	parthenolide	69-81	latexin	Homo sapiens	99-102	
21325821-8	2011	Targeting the NFkappaB pathway by Bay 11-7082 (IC(50)   10 muM) and parthenolide (IC(50)   30 muM) triggered suicidal erythrocyte death as shown by annexin V binding and decrease of forward scatter.	parthenolide	68-80	latexin	Homo sapiens	94-97