PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16447874-0 2005 [Effects of parthenolide on the activity and expression of urokinase type plasminogen activator in PGCL3 cells]. parthenolide 12-24 plasminogen activator, urokinase Homo sapiens 59-95 16447874-3 2005 RESULTS: Parthenolide could inhibit proliferation of PGCL3 cells after 24h treatment, the IC50 value was 17.60 micromol/L; Parthenolide reduced significantly the activity of uPA secreted by PGCL3 cells and down-regulated the expression level of uPA protein. parthenolide 123-135 plasminogen activator, urokinase Homo sapiens 245-248 16447874-4 2005 CONCLUSION: The antitumor activity of Parthenolide is involved in the activity and expression of urokinase type plasminogen activator. parthenolide 38-50 plasminogen activator, urokinase Homo sapiens 97-133 16447874-1 2005 OBJECTIVE: To study the effect of Parthenolide on the activity and expression of urokinase type plasminogen activator (uPA) on PGCL3 cells and to investigate the antitumor mechanisms of Parthenolide. parthenolide 34-46 plasminogen activator, urokinase Homo sapiens 81-117 16447874-1 2005 OBJECTIVE: To study the effect of Parthenolide on the activity and expression of urokinase type plasminogen activator (uPA) on PGCL3 cells and to investigate the antitumor mechanisms of Parthenolide. parthenolide 34-46 plasminogen activator, urokinase Homo sapiens 119-122 16447874-2 2005 METHODS: MTT assay was used to determine the growth inhibition by Parthenolide in PGCL3 cells; Effect of Parthenolide on the activity of uPA secreted by PGCL3 cells was measured by chromogenic substrate assay;The expression level of uPA protein was assessed by Western blot analysis. parthenolide 105-117 plasminogen activator, urokinase Homo sapiens 137-140 16447874-3 2005 RESULTS: Parthenolide could inhibit proliferation of PGCL3 cells after 24h treatment, the IC50 value was 17.60 micromol/L; Parthenolide reduced significantly the activity of uPA secreted by PGCL3 cells and down-regulated the expression level of uPA protein. parthenolide 9-21 plasminogen activator, urokinase Homo sapiens 174-177 16447874-3 2005 RESULTS: Parthenolide could inhibit proliferation of PGCL3 cells after 24h treatment, the IC50 value was 17.60 micromol/L; Parthenolide reduced significantly the activity of uPA secreted by PGCL3 cells and down-regulated the expression level of uPA protein. parthenolide 9-21 plasminogen activator, urokinase Homo sapiens 245-248 16447874-3 2005 RESULTS: Parthenolide could inhibit proliferation of PGCL3 cells after 24h treatment, the IC50 value was 17.60 micromol/L; Parthenolide reduced significantly the activity of uPA secreted by PGCL3 cells and down-regulated the expression level of uPA protein. parthenolide 123-135 plasminogen activator, urokinase Homo sapiens 174-177