PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27553015-8 2017 Moreover, TNF-alpha and IL-6 levels were significantly decreased in cortex and hippocampus of parthenolide-treated rats. parthenolide 94-106 interleukin 6 Rattus norvegicus 24-28 22004922-4 2011 The initial hypothermia was exaggerated; the second phase of the biphasic LPS-induced fever and circulating interleukin-6 (IL-6) and tumor necrosis factor alpha (TNFalpha) were significantly attenuated only in parthenolide-pretreated animals. parthenolide 210-222 interleukin 6 Rattus norvegicus 108-121 22004922-8 2011 In summary, pretreatment with parthenolide attenuates the febrile response during LPS-induced systemic inflammation by reducing circulating IL-6 and TNFalpha and decreasing hypothalamic NFkappaB/NF-IL6 activation, oxidative stress and expression of COX2. parthenolide 30-42 interleukin 6 Rattus norvegicus 140-144 20605167-6 2011 RESULTS: Both parthenolide and resveratrol treatment led to early significant increases in plasma levels of IL-6. parthenolide 14-26 interleukin 6 Rattus norvegicus 108-112 21223972-10 2011 Moreover, parthenolide attenuated the Ang II-induced expression of interleukin-6, a potent pro-hypertrophic fibroblast-derived factor. parthenolide 10-22 interleukin 6 Rattus norvegicus 67-80