PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17272824-7	2007	Parthenolide significantly inhibited IL-8 secretion induced by these cytokines and prevented NF-kappaB activation, IkappaBalpha degradation, and IkappaB Kinase complex activity.	parthenolide	0-12	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	115-127	
18235096-6	2008	Parthenolide, which prevents IkappaB-alpha degradation, inhibited TWEAK-induced NF-kappaB activation and prevented the aforementioned changes in vitro and in vivo.	parthenolide	0-12	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	29-42	
17272824-12	2007	We thus conclude that parthenolide inhibits IkappaB kinase, resulting in stabilization of cytoplasmic IkappaBalpha, which in turn leads to inhibition of NF-kappaB translocation and attenuation of subsequent inflammatory responses.	parthenolide	22-34	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	102-114	
16741149-4	2006	METHODS AND RESULTS: In vascular smooth muscle cells (VSMCs) and monocytes stimulated with lipopolysaccharide (LPS), nontoxic doses of PTN reduced IkappaBalpha degradation, NF-kappaB activation, and MCP-1 expression, without inhibiting AP-1 and MAPK.	parthenolide	135-138	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	147-159	
17436572-4	2007	In this report we present data to show that fenretinide (a synthetic retinoid) potentiates the apoptotic effects of parthenolide (a drug that inhibits the activation of NF-kappa B) and BAY 11-7085 (an inhibitor of I-kappa B-alpha kinase).	parthenolide	116-128	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	214-229