PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19428175-8	2009	Additionally, GA increased p21(Waf1/CIP1) expression in p53 null cancer cells, which was associated with GA-mediated impairing of the interaction between MDM2 and p21(Waf1/CIP1).	gambogic acid	14-16	MDM2 proto-oncogene	Homo sapiens	154-158	
19428175-0	2009	Gambogic acid down-regulates MDM2 oncogene and induces p21(Waf1/CIP1) expression independent of p53.	gambogic acid	0-13	MDM2 proto-oncogene	Homo sapiens	29-33	
19428175-2	2009	Although it was proved that GA enhances p53 protein level through inhibition of MDM2 in p53 wild-type cancer cells, the mechanisms of MDM2 inhibition especially with the absence of p53 are not fully understood.	gambogic acid	28-30	MDM2 proto-oncogene	Homo sapiens	80-84	
19428175-11	2009	It is concluded that GA down-regulates the MDM2 oncogene and exerts the anti-tumor activity independent of p53, and therefore provide more evidences for its therapeutic application.	gambogic acid	21-23	MDM2 proto-oncogene	Homo sapiens	43-47