PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12133425-4 2002 RESULTS: (1) Tripterine suppressed the development of proteinuria, decreased the level of serum anti-dsDNA antibodies, reduced the expressions of collagen type IV, fibronectin, TIMP-1, TIMP-2, TGF-beta(1) and improved the expressions of MMP-1, -2 in the murine kidney. celastrol 13-23 tissue inhibitor of metalloproteinase 1 Mus musculus 177-183 19356734-6 2009 Our data suggest that oral administration of celastrol suppresses ovalbumin-induced airway inflammation, hyperresponsiveness, and tissue remodeling by regulating the imbalance of MMP-2/-9 and TIMP-1/-2 by inflammatory cytokines via MAP kinases/NF-kappaB in inflammatory cells. celastrol 45-54 tissue inhibitor of metalloproteinase 1 Mus musculus 192-198