PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34549728-0	2021	PERK in POMC neurons connects celastrol with metabolism.	celastrol	30-39	pro-opiomelanocortin-alpha	Mus musculus	8-12	
34549728-7	2021	Our data extend these observations by demonstrating that celastrol-induced improvements in leptin sensitivity and energy balance were attenuated in mice with PERK deficiency in POMC neurons.	celastrol	57-66	pro-opiomelanocortin-alpha	Mus musculus	177-181	
35419676-0	2022	Celastrol Induces Apoptosis and Autophagy via the AKT/mTOR Signaling Pathway in the Pituitary ACTH-secreting Adenoma Cells.	celastrol	0-9	pro-opiomelanocortin-alpha	Mus musculus	94-98	
35419676-12	2022	CONCLUSION: Celastrol exerts potent antitumor effects on ACTH-secreting adenoma by downregulating the AKT/mTOR signaling in vitro and in vivo.	celastrol	12-21	pro-opiomelanocortin-alpha	Mus musculus	57-61