PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30093405-9 2018 Extending our in vitro observations, administration of celastrol to mice up-regulated cerebellar Hsp70. celastrol 55-64 heat shock protein 1B Mus musculus 97-102 30093405-6 2018 Pharmacological up-regulation of Hsp70 by the Hsp90 inhibitors celastrol and herbimycin A attenuated the aggregation of mutant PKCgamma in primary cultured Purkinje cells. celastrol 63-72 heat shock protein 1B Mus musculus 33-38 16909005-10 2005 HSP70 immunoreactivity was increased in lumbar spinal cord neurons of celastrol-treated G93A mice. celastrol 70-79 heat shock protein 1B Mus musculus 0-5 18202019-8 2008 However, celastrol (1-5 micromol/L) induced Hsp90 client protein degradation (Cdk4 and Akt) by 70% to 80% and increased Hsp70 expression by 12-fold. celastrol 9-18 heat shock protein 1B Mus musculus 120-125 24903326-12 2014 In addition, (b) using drugs (Celastrol or BGP-15) to increase Hsp70/Hsp110 levels protect cells against TBI, suggesting the beneficial effects of Hsp70/Hsp110 inducers to reduce the pathological consequences of TBI. celastrol 30-39 heat shock protein 1B Mus musculus 63-68 24903326-12 2014 In addition, (b) using drugs (Celastrol or BGP-15) to increase Hsp70/Hsp110 levels protect cells against TBI, suggesting the beneficial effects of Hsp70/Hsp110 inducers to reduce the pathological consequences of TBI. celastrol 30-39 heat shock protein 1B Mus musculus 147-152 19183864-4 2009 Although both arimoclomol and celastrol induced the expression of Hsp70, their effects on primary motoneurons in culture were significantly different. celastrol 30-39 heat shock protein 1B Mus musculus 66-71 19183864-6 2009 Immunostaining of celastrol-treated cultures for hsp70 and activated caspase-3 revealed that celastrol treatment activates both the heat shock response and the apoptotic cell death cascade. celastrol 18-27 heat shock protein 1B Mus musculus 49-54 19183864-6 2009 Immunostaining of celastrol-treated cultures for hsp70 and activated caspase-3 revealed that celastrol treatment activates both the heat shock response and the apoptotic cell death cascade. celastrol 93-102 heat shock protein 1B Mus musculus 49-54