PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24927548-2 2014 Two of the 50 predicted hits had activity against either human FPPS (HsFPPS) or Trypanosoma brucei FPPS (TbFPPS), the most active being the quinone methide celastrol (IC50 versus TbFPPS ~ 20 microM). celastrol 156-165 farnesyl diphosphate synthase Homo sapiens 63-67